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. 2021 Dec 7;4:1366. doi: 10.1038/s42003-021-02896-3

Table 1.

Roles of GV in CAN.

Metrics of GV Individuals Results References
Low blood glucose index and Under the curve 44 T1DM patients Significantly negative correlated with heart rate variability 49
SD and MAGE 20 T1DM patients Correlated with CAN 50
MAGE 133 young adults with T1DM Slightly increase heart rate variability 51
CV in CGM and all parameters of HbA1c 110 T2DM patients Independently associated with CAN 52
SD of HbA1c 681 T2DM patients Significantly associated with CAN 53
Visit-to-visit HbA1c 57 T2DM patients Inversely related to baroreflex sensitivity 54
Intrapersonal mean, SD, CV for HbA1c 238 T2DM patients Strongly associated with CAN 55
MAGE 48 men and 39 women with T2DM Increased GV was associated with CAN in women 56

CV coefficient of variation, SD standard deviation, T2DM type 2 diabetes mellitus, T1DM type 1 diabetes mellitus, HbA1c hemoglobin A1c, MAGE mean amplitude of glycemic excursion, CAN cardiovascular autonomic neuropathy.