Table 5.
Publication | Objective | Methods | Findings | Information Type |
Conclusion |
---|---|---|---|---|---|
Harrold, et al. [24] | Explore patient and provider views of ULDs for gout management. | Qualitative in-depth phone interviews of gout patients. | Patients understand use of allopurinol for reducing serum uric acid and preventing gout attacks, not clear on planned duration of therapy. Belief that allopurinol triggers or worsens gout, concerns about side effects. | treatment | Patients unaware of potential for flares upon ULD initiation as short-term side effect. |
Coburn, et al. [34] | Examine patient knowledge of gout, especially SUA goals including factors associated with that knowledge and the effects on health outcomes. | Survey of gout knowledge for VA patients over 19 that had started allopurinol in the previous 6 months. | Correct knowledge was high in patients for all topics except SU goal. | treatment, labs | SU goal knowledge was associated with more SU measurements during the first 2 years following ULT initiation. |
Becker & Chohan [38] | Identify and discuss factors contributing to suboptimal gout management with emphasis on immediate opportunities for improvement. | Editorial Review | Education about the disease is key: "diagnosis and course, the distinctive therapeutic modalities employed, circumstances likely to promote or mark progression, the significance of comorbid associations, and means to monitor therapy and maximize adherence to therapeutic recommendations". | pathophysiology, disease progression, treatment, labs | Patient education is key to improving clinical outcomes. |
Chandratre, et al. [19] | Explore patient perspectives on how gout impacts HRQOL. | Thematic analysis of focus group interviews about HRQOL. | Lack of information about acute attacks as side effect of allopurinol, interactions between medications for comorbidities. Incorrect advice to discontinue treatment. | treatment | Lack of knowledge about ULT benefits may lead to poor HRQOL. |
Doherty, et al. [4] | Identify and address why a 'curable' disease is so poorly managed. | Literature review searched the Medline database for articles published in English language using the search terms ‘gout’, ‘hyperuricaemia’, ‘hyperuricemia’, ‘tophi’ and ‘monosodium urate’ published after 1 January 1980, searched keywords 'therapy', 'management', 'cure', and 'treatment' alone and with the previous terms, other materials judged relevant. | Belief that gout refers to the acute attacks. | Lifestyle, treatment | Patients underestimate the importance of long-term ULT. |