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. 2021 Dec 7;8:19. doi: 10.1186/s40348-021-00132-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Multispectral optoacoustic tomography (MSOT) of vascular malformations. a Novel hybrid MSOT/US technique was shown to enable distinction of arteriovenous (AVM) from venous (VM) malformations as well as from healthy tissue by non-invasive, contrast-free, and radiation-free imaging of the lesions at the patients’ bedside. Further, as exemplarily shown for a patient receiving complete embolization of an AVM (b), MSOT/US depicted therapy response by showing a reduced signal of oxygenated and deoxygenated hemoglobin (c). ***p < 0.001. Figure adapted from Masthoff M, Helfen A, Claussen J, Karlas A, Markwardt NA, Ntziachristos V, Eisenblätter M, Wildgruber M. Use of Multispectral Optoacoustic Tomography to Diagnose Vascular Malformations. JAMA Dermatol. 2018 Dec 1;154(12):1457–1462. doi: 10.1001/jamadermatol.2018.3269. PMID: 30267083; PMCID: PMC6583374© 2018, American Medical Association