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. 2021 May 25;112(6):1069–1082. doi: 10.17269/s41997-020-00455-7

Table 2.

Projected cancer deaths, attributable or preventable cancer deaths, and cumulative preventable cancer deaths of selected lifestyle factors that are associated with cancers in Canada from 2024 to 2047 estimated using the OncoSim all-cancer model

Exposure Intervention targets/scenarios Projected cancer deaths* Preventable/attributable deaths** Cumulative preventable deaths†
Active smoking Base 72,934 26,446
10% reduction in smoking by 2032 72,200 734 6373
25% reduction in smoking by 2032 71,098 1836 15,934
50% reduction in smoking by 2032 69,262 3672 31,869
Price increases reduced smoking by 3.7% in 2018 71,016 1918 28,461
Reduce smoking prevalence to 5% by 2035 69,103 3831 33,158
WHO 2020 goal: 30% relative reduction in current smoking by 2020 70,731 2203 34,601
Passive smoking Base 23,453 278
10% reduction in secondhand smoking by 2032 23,425 28 276
25% reduction in secondhand smoking by 2032 23,384 70 690
50% reduction in secondhand smoking by 2032 23,314 139 1379
Alcohol Base 34,405 2809
Alcohol drinking prevalence decreases by 10% by 2032 34,124 281 4312
Alcohol drinking prevalence decreases by 25% by 2032 33,703 702 10,780
Alcohol drinking prevalence decreases by 50% by 2032 33,000 1405 21,557
Everyone who drinks > 1/day reduces 1 drink 33,062 1343 21,526
WCRF guideline 33,584 822 13,240
Canadian guideline 34,060 345 5756
Excess body weight Base 49,241 5604
Population BMI held at 2018 level 47,978 1264 9030
Population BMI reverted to 1994 distribution 46,199 3042 22,495
Population mean BMI reduced by 1.0 47,333 1909 13,792
Prevalence of overweight and obesity reduced by 5% by 2032 48,044 1198 8561
Prevalence of overweight and obesity reduced by 10% by 2032 47,180 2061 14,951
Prevalence of overweight and obesity reduced by 25% by 2032 45,612 3630 27,234
Inadequate physical activity Base 53,266 4898
10% reduction in inadequate physical activity by 2032 52,862 405 3309
25% reduction in inadequate physical activity by 2032 52,255 1012 8271
50% reduction in inadequate physical activity by 2032 51,243 2023 16,543
Sedentary behaviour Base 21,114 1975
10% reduction in sedentary time by 2032 20,926 188 1438
25% reduction in sedentary time by 2032 20,643 471 3595
50% reduction in sedentary time by 2032 20,172 942 7191
Low fruit consumption Base 58,821 5647
Everyone increases fruit intake by 1 serving/day 56,594 2227 43,500
Everyone increases fruit intake by 2 servings/day 54,849 3973 78,740
A relative 50% reduction in the prevalence of low fruit by 2032 55,998 2823 22,692
Low vegetable consumption Base 59,410 4297
Everyone increases vegetable intake by 1 serving/day 57,555 1855 37,012
Everyone increases vegetable intake by 2 servings/day 56,217 3192 65,959
A relative 50% reduction in the prevalence of low vegetable by 2032 57,262 2148 17,824
Processed meat Base 22,397 1094
Everyone reduces processed meat by 0.2 servings/week 22,226 170 3068
Everyone reduces processed meat by 0.5 servings/week 21,974 423 7629
Everyone reduces processed meat by 1 serving/week 21,563 834 15,065
Red meat Base 23,288 1849
Everyone reduces red meat by 0.5 servings/week 23,006 282 5012
Everyone reduces red meat by 1 serving/week 22,728 560 9958
Everyone reduces red meat by 2 servings/week 22,184 1104 19,655

BMI, body mass index; WCRF, World Cancer Research Fund; WHO, World Health Organization

*Projected cancer deaths from all cancer sites associated with the risk factor in 2047

**Attributable cancer deaths of base scenario in 2047, or preventable cancer deaths of interventions in 2047

†Cumulative preventable deaths from 2024 to 2047