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. 2021 May 25;112(6):1069–1082. doi: 10.17269/s41997-020-00455-7

Table 3.

Projected cancer deaths, attributable or preventable cancer deaths, and cumulative preventable cancer deaths of selected environmental factors and infections that are associated with cancers in Canada from 2024 to 2047 estimated using the OncoSim all-cancer model

Exposure Intervention targets/scenarios Projected cancer deaths* Preventable/attributable deaths** Cumulative preventable deaths†
Air pollution (PM2.5) Base 25,395 1360
Declining trend 25,145 250 2288
50% reduction off stabilized levels by 2036 25,032 363 2916
Radon Base 25,395 1735
Radon mitigation of above 100 Bq/m3 to 50 Bq/m3 by 2036 25,064 331 2832
Radon mitigation of above 200 Bq/m3 to 50 Bq/m3 by 2036 25,175 220 1841
UVR risk behaviours Base 2028 1190
UVR risk behaviours 10% reduction in UVR risk behaviours by 2037 1985 43 408
UVR risk behaviours 25% reduction in UVR risk behaviours by 2037 1916 112 1053
UVR risk behaviours 50% reduction in UVR risk behaviours by 2037 1784 244 2232
HBV Base 2484 219
HBV 10% reduction in the prevalence of HBV infection by 2027 2462 22 101
HBV 25% reduction in the prevalence of HBV infection by 2027 2429 55 253
HBV 50% reduction in the prevalence of HBV infection by 2027 2374 110 507
HCV Base 7223 385
HCV 10% reduction in the prevalence of HCV infection by 2027 7184 38 182
HCV 25% reduction in the prevalence of HCV infection by 2027 7127 96 453
HCV 50% reduction in the prevalence of HCV infection by 2027 7031 192 907
H. pylori Base 2361 1406
H. pylori 10% reduction in the prevalence of H. pylori infection by 2027 2221 141 611
H. pylori 25% reduction in the prevalence of H. pylori infection by 2027 2010 352 1528
H. pylori 50% reduction in the prevalence of H. pylori infection by 2027 1658 703 3056

Bq/m3, becquerels per cubic metre; HBV, hepatitis B virus; HCV, hepatitis C virus; H. pylori, Helicobacter pylori; PM2.5, particulate matter with a diameter of less than 2.5 μm; UVR, ultraviolet radiation

*Projected cancer deaths from all cancer sites associated with the risk factor in 2047

**Attributable cancer deaths of base scenario in 2047, or preventable cancer deaths of interventions in 2047

†Cumulative preventable deaths from 2024 to 2047