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. 2021 Nov 24;12:757508. doi: 10.3389/fphar.2021.757508

TABLE 1.

Patient clinical and biochemical characteristics.

Characteristics Total (n = 41) DKD non-ESRD group (n = 22) DKD ESRD group (n = 19)
Male, n. (%) 27 (65.85%) 16 (72.73%) 11 (57.89%)
Age (years) 65.39 ± 11.38 69.63 ± 13.01 61.89 ± 9.85
Blood pressures (mmHg)
 Systolic 158.49 ± 22.36 160.90 ± 21.98 156.00 ± 23.48
 Diastolic 82.63 ± 11.91 84.22 ± 13.1 79.47 ± 10.16
SCr (µmol/L) 372.90 ± 232.59 189.70 ± 74.64* 577.02 ± 164.35
eGFR (ml/min/1.73 m2) 22.91 ± 18.81 36.01 ± 16.77* 7.78 ± 2.37
24hU-pro (g/24 h) (IQR) 3.82 (1.38, 5.16) 3.00 (0.95, 5.7) 3.83 (1.94, 5.01)
HbA1c (%) 6.40 (5.56, 7.45) 6.90 (5.70, 7.60) 5.85 (5.38, 7.10)
UA (µmol/L) (IQR) 476.50 (370.00, 574.00) 451.00 (357.50, 574.00) 508.00 (434.00, 587.00)
BUN (mmol/L) (IQR) 17.70 (11.01, 24.47) 11.23 (8.36, 13.52)* 23.47 (20.48, 29.98)
Triglycerides (mmol/L) (IQR) 1.75 (1.16, 2.37) 1.63 (0.88, 2.03) 2.11 (1.42, 2.62)
Cholesterol (mmol/L) 5.18 ± 1.77 5.34 ± 1.82 4.97 ± 1.86
HDL (mmol/L) 1.13 ± 0.35 1.33 ± 0.59 1.03 ± 0.35
LDL (mmol/L) 3.42 ± 1.60 3.66 ± 1.71 3.13 ± 1.50
Serum albumin (g/L) 35.23 ± 5.65 34.44 ± 6.72 36.10 ± 3.84
AST (U/L) (IQR) 16.00 (13.00, 20.00) 17.00 (13.00, 21.00) 16.00 (11.00, 20.50)
ALT (U/L) (IQR) 12.00 (9.00, 21.00) 14.00 (10.75, 21.25) 9.00 (7.00, 16.00)

Note. Abbreviations: SCr, serum creatinine; eGFR, estimated glomerular filtration rate; 24hU-pro, 24-h urinary protein quantity; UA, uric acid; BUN, blood urea nitrogen; LDL, low-density lipoprotein; HDL, high-density lipoprotein; AST, glutamic oxaloacetic transaminase; ALT, alanine aminotransferase; IQR, interquartile range; DKD, diabetic kidney disease; ESRD, end-stage renal disease.

*p < 0.05 vs. DKD ESRD group.