Table 3.
Predictors (blocked regression) of cardiovascular measures in overall sample (N = 280).
| Dependent measure | Significant predictors | Standardized beta value (odds ratio) | Cumulative adjusted r [2] or Nagelkerke r [2] | t or Wald (p) |
|---|---|---|---|---|
| Blood pressure | ||||
| Systolic BP (mm Hg) F(3,275) = 15.24, p < .000 | BMI ¶ Age ¶ Cannabis days past mo. (log10) |
.243 .269 .117 |
.063 .123 .133 |
4.33 (.000) 4.76 (.000) 2.06 (.040) |
| Diastolic BP (mm Hg) F(3,275) = 17.13, p < .000 | Age ¶ BMI Avg. daily alcohol use (log10) |
.292 .207 .127 |
.091 .135 .148 |
5.26 (.000) 3.72 (.000) 2.28 (.023) |
| Heart rate | ||||
| Seated HR (bpm) F(1,278) = 6.15, p = .014 | Heroin days past mo. | –.147 | .018 | −2.48 (.014) |
| Supine HR (bpm) F(4,275) = 7.70, p = .000 | BMI Avg. daily alcohol use (log10) Years regular alcohol use Cannabis days past mo. (log10) |
.110 .269 –.201 –.131 |
.013 .044 .075 .088 |
1.91 (.057) 4.39 (.000) −3.36 (.001) −2.20 (.027) |
| Sinus bradycardia (%) (<60 bpm) | Avg. daily alcohol use (log10) Years regular cannabis use Heroin days past mo. |
–.225 1.024 1.021 |
.107 | 10.42 (.001) 5.80 (.016) 4.24 (.040) |
| Profound bradycardia (%) (<50 bpm) | Tobacco days past mo. (log10) | –.277 | .073 | 5.72 (.017) |
| ECG | ||||
| QRS duration (ms) F(3,276) = 12.56, p < .000 | Race (whites longer QRS) Sex (males longer QRS) BMI |
.274 .171 .133 |
.069 .096 .111 |
4.80 (.000) 3.02 (.003) 2.34 (.020) |
| QT interval (ms) F(2,277) = 6.43, p < .002 | Avg. daily alcohol use (log10) Tobacco days past mo. (log10) |
–.204 .145 |
.022 .041 |
−3.30 (.001) 2.36 (.019) |
| QTc interval (ms) F(6,273) = 7.77, p < .000 | BMI Sex (males shorter QTc) Avg. daily cannabis use (log10) Tobacco days past mo. (log10) Cocaine days past mo. Years regular cocaine use |
.225 –.158 –.152 –.310 .421 .122 |
.046 .072 .089 .104 .117 .127 |
3.99 (.000) −2.79 (.006) −2.66 (.008) −1.92 (.056) 2.68 (.008) 2.00 (.047) |
| PR interval (ms) F(1,278) = 7.75, p = .006 | BMI | .165 | .024 | 2.78 (.006) |
| P-wave duration (ms) F(2,277) = 7.37, p = .001 | BMI Race (whites shorter P-wave) |
.178 –.118 |
.037 .044 |
3.03 (.003) −2.00 (.047) |
| Sinus arrhythmia (%) | Race (whites more SA) | .404 | .040 | 5.61 (.018) |
| Left ventricular hypertrophy (%) | Race (whites more LVH) Heroin days past mo. |
2.344 –.969 |
.091 | 3.77 (.052) 5.09 (.024) |
* Each table entry indicates a predictor variable that was significantly associated with the outcome (left column; omnibus model statistics shown) in regression analysis. N.S. indicates no significant findings. F = females, M = males, B = black, W = white, and BMI = body mass index.
¶ Indicates predictor also significant for clinical threshold (Systolic BP ≥ 140, Diastolic BP ≥ 90).