Table 3.
Studies describing the efficacy of antimicrobial coatings based on chitosans associated with silver and ceramics.
CS-based coatings | Material | Medical application | Species | Major conclusions | Reference |
---|---|---|---|---|---|
Silver nanoparticles (AgNPs)/polyvinylpyrrolidone (PVP) | Silicone wafers and polyethylene sheetsa,b | Medical devices |
E. colie S. aureusf |
Chitosan-AgNPs/PVP composites displayed higher antimicrobial activity than polyethylene films (inhibition zone 4 mm vs. 0 mm, respectively). In addition, these films reduced S. aureus and E. coli adhesion up to 100%. | (Wang et al., 2012a) c |
Catechol/Silver nanoparticles | Polyurethane filmsa,b | Urethral catheters |
E. colie S. aureusf |
During the initial adhesion, live E. coli cells significantly decreased in the CS-catechol hydrogel-coated films, and further decreased in the CS-catechol/AgNPs-coated films compared to the bare substrate (bare: 85.23%, CS-catechol hydrogel coating: 48.32%, CS-catechol hydrogel coating with AgNPs: 4.70%). | (Yang et al., 2019) c |
Zinc oxide/polyaniline (ZnO/PANI) composite | Glassa | Indwelling medical devices |
C. albicansg P. aeruginosah S. aureusf |
CS-ZnO/PANI coatings inhibited S. aureus and P. aeruginosa biofilm formation by more than 95%. The antimicrobial activity of CS–ZnO/PANI composite against established biofilms resulted in more than 95% inhibition. | (Pandiselvi and Thambidurai, 2015) d |
Iron oxide nanoparticles | Polystyrene microtiter platesa | Orthopedic implants | S. aureusf | CS-coated iron oxide nanoparticles decreased the number of biofilm cells up to 3 Log and its metabolic activity by 50% compared to the control. | (Shi et al., 2016)n.d. |
Apatite | Titanium surfacesa | Orthopedic implants |
E. colie S. aureusf |
Apatite-CS films reduced biofilms viability by 1 and 2 Log for E. coli and S. aureus, respectively, after 48 h of exposure. | (Visan et al., 2016) |
in vitro study.
study performed under hydrodynamic conditions.
dip coating.
non-immobilized CS.
Escherichia sp.
Staphylococcus sp.
Candida sp.
Pseudomonas sp.