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. 2021 Nov 22;24(12):103480. doi: 10.1016/j.isci.2021.103480

Table 3.

Studies describing the efficacy of antimicrobial coatings based on chitosans associated with silver and ceramics.

CS-based coatings Material Medical application Species Major conclusions Reference
Silver nanoparticles (AgNPs)/polyvinylpyrrolidone (PVP) Silicone wafers and polyethylene sheetsa,b Medical devices E. colie
S. aureusf
Chitosan-AgNPs/PVP composites displayed higher antimicrobial activity than polyethylene films (inhibition zone 4 mm vs. 0 mm, respectively). In addition, these films reduced S. aureus and E. coli adhesion up to 100%. (Wang et al., 2012a) c
Catechol/Silver nanoparticles Polyurethane filmsa,b Urethral catheters E. colie
S. aureusf
During the initial adhesion, live E. coli cells significantly decreased in the CS-catechol hydrogel-coated films, and further decreased in the CS-catechol/AgNPs-coated films compared to the bare substrate (bare: 85.23%, CS-catechol hydrogel coating: 48.32%, CS-catechol hydrogel coating with AgNPs: 4.70%). (Yang et al., 2019) c
Zinc oxide/polyaniline (ZnO/PANI) composite Glassa Indwelling medical devices C. albicansg
P. aeruginosah
S. aureusf
CS-ZnO/PANI coatings inhibited S. aureus and P. aeruginosa biofilm formation by more than 95%. The antimicrobial activity of CS–ZnO/PANI composite against established biofilms resulted in more than 95% inhibition. (Pandiselvi and Thambidurai, 2015) d
Iron oxide nanoparticles Polystyrene microtiter platesa Orthopedic implants S. aureusf CS-coated iron oxide nanoparticles decreased the number of biofilm cells up to 3 Log and its metabolic activity by 50% compared to the control. (Shi et al., 2016)n.d.
Apatite Titanium surfacesa Orthopedic implants E. colie
S. aureusf
Apatite-CS films reduced biofilms viability by 1 and 2 Log for E. coli and S. aureus, respectively, after 48 h of exposure. (Visan et al., 2016)
a

in vitro study.

b

study performed under hydrodynamic conditions.

c

dip coating.

d

non-immobilized CS.

e

Escherichia sp.

f

Staphylococcus sp.

g

Candida sp.

h

Pseudomonas sp.