FIGURE 7.

(A) Concentrations of TNF-α and IL-6 and (B) components of the inflammatory pathway in the liver tissue of mice after 8 weeks of HFD feeding, (C) and in AML12 cells incubated without or with FFA and different concentrations of HX (6.25, 12.50, and 25.00 mg/ml). A one-way ANOVA was used, and multiple comparisons were employed, and the results are expressed as the mean ± SEM (n = 6 per group). Statistical analyses were performed using Student’s t test. Different lowercase letters denote significant differences among groups (p < 0.05). TNF-α, tumor necrosis factor-α; IL-6, interleukin-6; IKK, inhibitor of κB kinase; NF-κB, nuclear factor-ĸB; IκB, inhibitor of NF-κB; p-IκB, phosphorylation inhibitor of NF-κB; p-NF-κB, phosphorylation nuclear factor-ĸB; CON, control; HFD, high-fat diet; HX, Huo Xiang.