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Evolution timeline of in silico scale-specific and multi-scale data-drive cancer models. Timeline of salient in silico scale-specific and multi-scale cancer models, along with PubMed yearly report (1990-2020) to display the evolutionary trends seen in the development of (A) genome-scale cancer models, (B) Transcript-level cancer models, (C) Proteome-scale models, (D) Metabolome scale models, (E) Environment-based models, (F) Cell-level models, and (G) Multi-scale cancer models.
