Table 2.
CMV status in cholestatic and non-cholestatic infants.
| Cholestatic (n = 45)a | Non-cholestatic (n = 24)a | p b | |
|---|---|---|---|
| Maternal CMV serostatus | |||
| IgG +, IgM − | 23/34 (68) | 11/16 (69) | 1.00 |
| IgG +, IgM + | 2/34 (6) | 0/16 (0) | 1.00 |
| IgG −, IgM + | 1/34 (3) | 0/16 (0) | 1.00 |
| IgG −, IgM − | 8/34 (24) | 5/16 (31) | 0.73 |
| Infant CMV DNA PCR | |||
| Sedimented whole blood + | 12/45 (27) | 3/24 (13) | 0.23 |
| Urine + | 6/30 (20) | 0/21 (0) | 0.036* |
| Plasma + | 27/45 (60) | 0/18 (0) | 0.000007* |
| Positive in any sample | 31/45 (69) | 3/24 (13) | <0.000009* |
| Age at blood sampling, days |
32 (19, 41), n = 41 |
29 (27, 38), n = 22 |
0.53 |
CMV, cytomegalovirus; IgG, immunoglobulin G; IgM, immunoglobulin M.
a
n/N (%) for proportions, median ([IQR:] 25th percentile, 75th percentile) for continuous variables.
b
Fisher exact test for proportions, Mann–Whitney U-test for continuous variables.
*
Statistical significance.