Table 4.

CMV and risk factors for cholestasis, multivariate analysis.

	Crude OR	95% CI	p	Adjusted OR	95% CI	p
CMV DNA positivea	15.5	4.0, 60.7	0.000082*	5.5	1.1, 26.6	0.036*
PN ≥2 weeksb	16.6	4.0, 68.5	0.00011*	29.6	2.3, 377.4	0.0091*
Necrotizing enterocolitisc	18.4	2.3, 148.3	0.0062*	6.4	0.66, 61.7	0.11
Gestational aged	1.14	0.94, 1.38	0.18	1.41	0.98, 2.02	0.065

Multivariable logistic regression model for positive CMV DNA adjusted for known risk factors for cholestasis. Nagelkerke R square for model: 0.61.

^aCMV DNA positive in sedimented whole blood, plasma or urine. Reference: CMV DNA negative in all locations.

^bReference: PN <2 weeks.

^cReference: No diagnosis of necrotizing enterocolitis ≥Bell's stage 2.

^dPer additional day of gestational age.

OR, odds ratio; CI, confidence interval; CMV, cytomegalovirus; DNA, deoxyribonucleic acid; PN, parenteral nutrition.