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. 2021 Nov 24;12:786602. doi: 10.3389/fimmu.2021.786602

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Copyright © 2021 Sun, Huang, Zheng, Liu, Yang, Guo, Kong, Lv, Zhou, Du, Jiang and Jiang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GBS has a slight impact on the number of neutrophils. The number of neutrophils in peripheral blood (A) and peritoneal lavage fluid (B) from WT and Fpr2^-/- mice, sampled 3h after i.p. injection of heat-killed GBS (0.5 mg/mouse). (C) The blocking effects evaluation of three doses of DPPC on neutrophils (% of CD45⁺ cells) after GBS-infection in WT mice. (D) Blocked by DPPC, difference in the number of neutrophils (% of CD45⁺ cells) between WT and Fpr2^-/- groups observed after injecting the GBS. Data are representative of three independent experiments with n = 5 mice per group. Data are shown as mean ± SD. *P < 0.05, **P < 0.01, ns means non sense.