TABLE 2.
GO term analysis for AS-NMD regulated genes in mouse.
| GOTerm | Adjusted p-value | Number of genes |
|---|---|---|
| RNA binding | 0.0000 | 104 |
| mRNA binding | 0.0000 | 38 |
| Ubiquitin protein ligase binding | 0.0003 | 19 |
| Pre-mRNA binding | 0.0000 | 14 |
| mRNA 3′-UTR binding | 0.0000 | 14 |
| RNA polymerase II-specific DNA-binding transcription factor binding | 0.0175 | 13 |
| Active ion transmembrane transporter activity | 0.0078 | 13 |
| Active ion transmembrane transporter activity | 0.0022 | 13 |
| Proton transmembrane transporter activity | 0.0022 | 11 |
| Single-stranded DNA binding | 0.0000 | 11 |
| Hormone receptor binding | 0.0175 | 10 |
| Single-stranded RNA binding | 0.0002 | 10 |
| Nuclease activity | 0.0310 | 10 |
| Nucleotidyltransferase activity | 0.0215 | 9 |
| rRNA binding | 0.0008 | 8 |
| Helicase activity | 0.0284 | 8 |
| Ubiquitin-like protein-specific protease activity | 0.0153 | 7 |
| Translation factor activity, RNA binding | 0.0087 | 7 |
| Nuclear receptor binding | 0.0175 | 7 |
| Ribonuclease activity | 0.0310 | 7 |
| Antiporter activity | 0.0078 | 6 |
| Antiporter activity | 0.0022 | 6 |
| ATPase-coupled cation transmembrane transporter activity | 0.0022 | 6 |
| Regulatory RNA binding | 0.0000 | 6 |
| tRNA binding | 0.0168 | 5 |
| RNA helicase activity | 0.0284 | 5 |
| Poly-pyrimidine tract binding | 0.0002 | 5 |
| Poly-purine tract binding | 0.0002 | 5 |
| 3′-5′ exonuclease activity | 0.0310 | 5 |
| Exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5′-phosphomonoesters | 0.0310 | 5 |
| Telomeric DNA binding | 0.0000 | 5 |
| Phosphatidylinositol-3-phosphate binding | 0.0208 | 4 |
| Ionotropic glutamate receptor binding | 0.0160 | 4 |
| Ubiquitin-like protein conjugating enzyme activity | 0.0195 | 4 |
| snRNA binding | 0.0164 | 4 |
| Translation elongation factor activity | 0.0087 | 4 |
| Pre-mRNA 3′-splice site binding | 0.0000 | 4 |
| Ion transmembrane transporter activity, phosphorylative mechanism | 0.0022 | 4 |
| Cholesterol transfer activity | 0.0159 | 3 |
| Hexosaminidase activity | 0.0105 | 3 |
| Intramolecular oxidoreductase activity, interconverting aldoses and ketoses | 0.0023 | 3 |
| 5S rRNA binding | 0.0008 | 3 |
| Pre-mRNA intronic binding | 0.0004 | 3 |
| mRNA CDS binding | 0.0004 | 3 |
| Anion:anion antiporter activity | 0.0078 | 3 |
| Sequence-specific single stranded DNA binding | 0.0000 | 3 |
| Large ribosomal subunit rRNA binding | 0.0205 | 2 |
| 5′-nucleotidase activity | 0.0281 | 2 |
| Uridylyltransferase activity | 0.0156 | 2 |
| C-rich single-stranded DNA binding | 0.0034 | 2 |
| Poly(G) binding | 0.0002 | 2 |
| Voltage-gated chloride channel activity | 0.0078 | 2 |
| Regulatory region RNA binding | 0.0000 | 2 |
| N6-methyladenosine-containing RNA binding | 0.0000 | 2 |
| Positive regulation of telomerase RNA reverse transcriptase activity | 0.0000 | 2 |
| G-rich strand telomeric DNA binding | 0.0000 | 2 |