TABLE 3.
GO term analysis for AS-NMD regulated genes in Drosophila.
| GOTerm | Adjusted p-value | Number of genes |
|---|---|---|
| Metal ion binding | 0.0022 | 74 |
| Nucleotide binding | 0.0076 | 52 |
| RNA binding | 0.0022 | 36 |
| Poly(A) RNA binding | 0.0022 | 22 |
| mRNA binding | 0.0022 | 19 |
| Substrate-specific channel activity | 0.0078 | 14 |
| Ion channel activity | 0.0078 | 14 |
| Calcium ion binding | 0.0096 | 13 |
| Metal ion transmembrane transporter activity | 0.0078 | 13 |
| Gated channel activity | 0.0078 | 12 |
| Actin binding | 0.0051 | 11 |
| Cation channel activity | 0.0078 | 10 |
| Kinase binding | 0.0092 | 6 |
| Divalent inorganic cation transmembrane transporter activity | 0.0078 | 6 |
| Adenylate cyclase activity | 0.0024 | 5 |
| Glutamate receptor activity | 0.0048 | 5 |
| Calcium ion transmembrane transporter activity | 0.0078 | 5 |
| Pre-mRNA binding | 0.0029 | 4 |
| Calcium-dependent phospholipid binding | 0.0101 | 3 |
| Translation regulator activity, nucleic acid binding | 0.0079 | 3 |
| Peptidase activator activity | 0.0035 | 3 |
| Intracellular ligand-gated ion channel activity | 0.0078 | 3 |
| Tau-protein kinase activity | 0.0050 | 2 |
| Voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential | 0.0050 | 2 |
| Voltage-gated sodium channel activity | 0.0050 | 2 |
| Cysteine-type endopeptidase activator activity involved in apoptotic process | 0.0035 | 2 |
| Peptidase activator activity involved in apoptotic process | 0.0035 | 2 |
| Cholesterol binding | 0.0048 | 2 |
| Glutamate binding | 0.0048 | 2 |
| Ligand-gated calcium channel activity | 0.0078 | 2 |
| Calcium-release channel activity | 0.0078 | 2 |
| Calcium: cation antiporter activity | 0.0078 | 2 |
| Store-operated calcium channel activity | 0.0078 | 2 |