Table 4.
Age-dependent change in bone parameters (μCT) in male Sprague-Dawley rats depending upon the diet (values are ratio of 74/24 parameters and presented as percent change).
| Change | Whey | Soy | p -value |
|---|---|---|---|
| Total length | +26 | +21 | 0.01 |
| Tt. % BV/TV | +0.008 | +0.02 | 0.65 |
| vBMD | +83 | +59 | 0.001 |
| Dia.Dia | +24 | +14 | 0.002 |
| Med.Dia | +98 | +6 | 0.07 |
| Ct.Th | +62 | +24 | <0.001 |
| MOI I min | +177 | +173 | <0.001 |
| MOI polar | +180 | +182 | <0.001 |
| MOI areal | +109 | +55 | <0.001 |
| Tb.BV/TV | +8 | −14 | 0.086 |
| Tb.Conn.D | +19 | −13 | 0.045 |
| Tb.SMI | −20 | +19 | 0.01 |
| Tb.N | +4 | −16 | 0.3 |
| Tb.Th | NC | NC | 0.85 |
| Tb.Sp | +4 | +20 | 0.4 |
NC, no change; BV/TV, bone volume/total volume; vBMD, bone volumetric bone mineral density; Tt.Ar, total area; Ct.Ar, cortical area; Ct.Ar/Tt.Ar, cortical area fraction; Ct.Th, cortical thickness; Dia.Dia, diaphyseal diameter; Med.Dia, medullary diameter; MOI, moment of inertia; Conn.D, connectivity density; I min, minimum moment of inertia; SMI, structure model index; Tb.Th, trabecular thickness; Tb.N, trabecular number; Tb.Sp, trabecular separation.