Table 1.
Patients and Treatment Characteristics.
| Characteristics | |
|---|---|
| Number of patients (n) | 152 |
| Gender (n) | |
| Female | 65 |
| Male | 87 |
| Age at diagnosis (median, 1.-3. IQR) | 66 (IQR 54-75) |
| Histopathology (n) | |
| Adenocarcinoma | 43 |
| Sinonasal melanoma | 39 |
| Squamous cell carcinoma | 21 |
| Olfactory neuroblastoma | 18 |
| Adenoidcystic carcinoma | 16 |
| Sinonasal undifferentiated carcinoma | 15 |
| Tumor epicenter | |
| Ethmoid sinus | 80 |
| Nasal cavity | 55 |
| Maxillary sinus | 17 |
| Initial clinical T classification according to clinical and radiological assessment (n) | |
| cT1 | 3 |
| cT2 | 28 |
| cT3 | 48 |
| cT4a | 27 |
| cT4b | 46 |
| Initial N classification (n) | |
| cN0 | 144 |
| cN1 | 3 |
| cN2b | 1 |
| cN2c | 4 |
| N3a | 0 |
| N3b | 0 |
| Initial M classification (n) | |
| cM0 | 146 |
| cM1 | 6 |
| Primary treatment protocol (n) | |
| Curative | 137 |
| Surgical tumor resection | 124 |
| Primary radio(chemo)therapy using IMRT or PT | 13 |
| Palliative | 15 |
| Palliative radiotherapy | 7 |
| Palliative debulking | 6 |
| Best supportive care | 2 |
| Surgical approach (n = 124) | |
| Endoscopic endonasal only | 85 |
| Transfacial only | 20 |
| Craniofacial | 12 |
| Combined endoscopic endonasal + transfacial/craniofacial | 7 |
Abbreviations: IQR, interquartile range; IMRT, intensity-modulated radiation therapy; PT, proton beam therapy.