TABLE 1.
Clinical Characteristics of All Patients
| Characteristic | All Patients |
|---|---|
| n = 27 (100%) | |
| Baseline and demographics | |
| Age (years), mean (range) | 59 (20‐80) |
| Sex | 7 females |
| 20 males | |
| BMI, mean (range) | 27.3 (21.5‐37.7) |
| Comorbidities | |
| Obesity (%) | 7 (25.9) |
| DM (%) | 6 (22.2) |
| Symptoms and hospital course | |
| O2 saturation at admission | 94 (69‐100) |
| Supplemental O2 (%) | 27 (100) |
| Invasive mechanical ventilation | 23 (85.2) |
| Previous medications received | |
| ACE inhibitor | 6 (22.2) |
| Captopril | 5 (18.5) |
| Enalopril/hydrochlorothiazide | 1 (3.7) |
| Antiarrhythmic | |
| Amiodarone | 1 (3.7) |
| Antibiotics | |
| Amoxicillin | 2 (7.4) |
| Azithromycin | 15 (55.5) |
| Ceftriaxone | 20 (74.1) |
| Cephalexin | 1 (3.7) |
| Cephepime | 1 (3.7) |
| Clarithromycin | 6 (22.2) |
| Clindamycin | 1 (3.7) |
| Piperacillin/tazobactam | 1 (3.7) |
| Vancomycin | 1 (3.7) |
| Antiretrovirals | 0 (0) |
| Immunobiologics | 0 (0) |
| Bronchodilators (fenoterol, ipratropium, aminophylline) | 1 (3.7) |
| Ibuprofen | 1 (3.7) |
| Statin (simvastatin) | 1 (3.7) |
| Steroids (hydrocortisone) | 1 (3.7) |
| Medications received during day 1 | |
| ACE inhibitor (captopril) | 2 (7.4) |
| Antibiotics | 27 (100) |
| Amoxicillin | 0 (0) |
| Azithromycin | 22 (81.5) |
| Ceftriaxone | 0 (0) |
| Cephalexin | 0 (0) |
| Cephepime | 0 (0) |
| Clarithromycin | 4 (14.8) |
| Clindamycin | 1 (3.7) |
| Piperacillin/tazobactam | 1 (3.7) |
| Vancomycin | 0 (0) |
| Anticoagulation | 18 (66.7) |
| Enoxaparin | 15 (55.5) |
| Heparin | 4 (14.8) |
| Antivirals (Tamiflu) | 22 (81.5) |
| Bronchodilators | 0 (0) |
| Insulin | 3 (11.1) |
| Steroids | 4 (14.8) |
| Hydrocortisone | 2 (7.4) |
| Prednisone | 1 (3.7) |
| Methylprednisone | 1 (3.7) |
| Vasopressors | 14 (51.8) |
| Dobutamine | 0 (0) |
| Dopamine | 0 (0) |
| Norepinephrine | 14 (51.8) |
| Laboratory values, mean (range)/number | |
| AST (units/L) | 92.2 (29.3‐343)/13 |
| ALT (IU/L) | 100.61 (22.1‐533.3)/15 |
| Total bilirubin (mg/dL) | 1.13 (0.15‐3.08)/14 |
| Hemoglobin (g/dL) | 11.0 (6.2‐14.5)/27 |
| Platelets (103/μL) | 217.8 (25‐437)/27 |
| Leukocytes (103/μL) | 12.4 (5.2‐32.0)/27 |
| Creatinine (mg/dL) | 3.7 (0.63‐16.3)/27 |