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. 2021 Nov 25;74(3):213–220. doi: 10.1002/iub.2577

TABLE 1.

Unfolding Gibbs free energies of mutations calculated using PremPS server depicting change in protein complex stability upon mutation

Mutation position ΔΔG Effect of mutation
D215V −0.4 Stabilizing
A222V −0.84 Stabilizing
G261C 0.06 Mild stabilizing
E484G −0.16 Stabilizing
D614G −0.31 Stabilizing
Q860V −0.94 Stabilizing
K861L −0.77 Stabilizing
S970F −1 Stabilizing