TABLE 1.
Characteristic | 2019 (n = 223) | 2020 (n = 150) | Significance |
---|---|---|---|
Mean age (SD) | 67.2 (11.4) | 66.0 (11.1) | 0.313 |
Gender (% of cohort) | 0.770 | ||
Male | 165 (74%) | 113 (75.3%) | |
Female | 58 (26%) | 37 (24.7%) | |
Primary malignancy (% of cohort) | |||
Oropharynx | 87 (39.0%) | 44 (29.3%) | 0.055 |
Oral cavity | 57 (25.6%) | 35 (23.3%) | 0.625 |
Larynx | 47 (21.1%) | 29 (19.3%) | 0.697 |
Hypopharynx | 15 (6.7%) | 25 (16.7%) | 0.003 |
Nasopharynx | 3 (1.3%) | 2 (1.3%) | 1.000 |
Others | 14 (5.2%) | 14 (9.3%) | 0.210 |
TNM staging, AJCC seventh edition (% of cohort) | |||
T0 | 4 (1.8%) | 5 (3.4%) | 0.493 |
T1 | 81 (36.3%) | 37 (25.0%) | 0.022 |
T2 | 57 (25.6%) | 27 (18.2%) | 0.099 |
T3 | 32 (14.3%) | 25 (16.9%) | 0.506 |
T4 | 49 (22.0%) | 54 (36.5%) | 0.002 |
N0 | 100 (44.8%) | 58 (38.9%) | 0.258 |
N1 | 12 (5.4%) | 10 (6.7%) | 0.594 |
N2 | 105 (47.1%) | 74 (49.7%) | 0.626 |
N3 | 6 (2.7%) | 7 (4.7%) | 0.302 |
M | 0.296 | ||
0 | 217 (97.3%) | 141 (95.3%) | |
1 | 6 (2.7%) | 7 (4.7%) | |
Overall staging, AJCC seventh edition (% of cohort) | |||
I | 26 (25.1%) | 21 (14.0%) | 0.009 |
II | 18 (8.1%) | 9 (6.0%) | 0.449 |
III | 21 (9.4%) | 18 (12.0%) | 0.424 |
IV | 128 (57.4%) | 101 (67.3%) | 0.053 |
IVa | 109 (48.9%) | 76 (50.7%) | 0.735 |
IVb | 13 (5.8%) | 20 (13.3%) | 0.012 |
IVc | 6 (2.7%) | 5 (3.3%) | 0.761 |
Treatment intent | |||
Radical | 190 (85.2%) | 118 (78.7%) | |
Palliative | 33 (14.8%) | 32 (21.3%) | |
Treatment modality | |||
Radical surgery only | 69 (30.9%) | 30 (20.0%) | 0.023 |
Surgery + adjuvant (chemo)radiotherapy | 48 (23.5%) | 40 (26.7%) | 0.752 |
Radical (chemo)radiotherapy | 67 (30.0%) | 47 (31.3%) | 0.876 |
Palliative radiotherapy | 19 (8.5%) | 15 (10.0%) | 0.626 |
Palliative chemotherapy | 0 | 1 (0.7%) | 0.402 |
Best supportive care | 16 (7.2%) | 13 (8.7%) | 0.598 |
Bold values indicate significant differences (p < 0.05).