TABLE 3.

Growth inhibitory effects of 7m on LO2 and MCF7/Tax cells.

Compound	IC50 ± SD (nM) a			Selectivity ratio b	Resistant fold c
	MCF7	MCF7/Tax	LO2
7m	183 ± 32	213 ± 26	890 ± 14	4.9	1.2
CA-4	11.4 ± 0.2	21.2 ± 0.6	15.2 ± 0.5	1.3	1.9
Taxol	24.6 ± 3.2	336 ± 18	32.4 ± 1.9	1.3	13.7

^aNote. Each compound was tested in triplicate; the data are presented as the mean ± SD.

^bSelectivity ratio = (IC₅₀ human normal cells LO2)/(IC₅₀ MCF7).

^cResistant fold = (IC₅₀ MCF7/Tax)/(IC₅₀ MCF7).