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. 2000 Apr;38(4):1688–1693. doi: 10.1128/jcm.38.4.1688-1693.2000

TABLE 2.

Isolates susceptible, intermediate, or resistant as determined by caliper and Sirscan readings of zone diameters

Antibiotic(s) Isolate(s) NCCLS breakpoints (mm) No. tested SIc/SIsa Rc/Rsb SIc/Rsc Rc/SIsd Zone size(s) (mm) of Rc/SIs isolate(s)e % of results that were very major errorsf
Amoxicillin-clavulanate Staphylococcus sp. ≥20 127 102 19 1 5 20 (S), 20 (S), 20 (S), 21 (S), 22 (S) 3.9
Gram-negative bacilli 14–17 87 73 14 0 0
Ampicillin Gram-negative bacilli 14–16 209 87 122 0 0
Aztreonam Gram-negative bacilli 16–21 241 219 18 0 4 16 (I), 17 (I), 17 (I), 17 (I)
Cefotaxime Gram-negative bacilli 15–22 209 197 10 1 1 15 (I)
Cefuroxime sodium Gram-negative bacilli 15–17 209 171 37 0 1 18 (S) 0.5
Cephalothin Gram-negative bacilli 15–17 210 128 75 7 0
Ciprofloxacin Gram-negative bacilli and Staphylococcus sp. 16–20 278 221 56 0 1 17 (I)
Clindamycin Staphylococcus sp. 15–20 127 99 28 0 0
Erythromycin Staphylococcus sp. 14–22 127 46 79 0 2 14 (I), 14 (I)
Gentamicin Gram-negative bacilli and Staphylococcus sp. 13–14 364 326 35 1 2 14 (I), 14 (I)
Imipenem Gram-negative bacilli 14–15 241 233 8 0 0
Mezlocillin Pseudomonas sp. ≥16 28 18 10 0 0
Other gram-negative bacilli 18–20 212 159 48 4 1 18 (I)
Nitrofurantoin Gram-negative bacilli and Staphylococcus sp. 15–16 115 92 18 0 5 15 (I), 15 (I), 15 (I), 15 (I), 15 (I)
Norfloxacin Gram-negative bacilli 18–20 87 1 86 0 0
Oxacillin Coagulase-negative staphylococci ≥18 74 19 53 0 2 22 (S), 25 (S) 2.7
S. aureus 11–12 53 38 15 0 0
Penicillin G Staphylococcus sp. 28–29 127 115 12 0 0
Piperacillin Pseudomonas sp. ≥18 28 26 1 0 1 19 (S) 3.6
Other gram-negative bacilli 18–20 124 92 31 1 0
Trimethoprim-sulfamethoxazole Gram-negative bacilli and Staphylococcus sp. 11–15 366 266 96 2 2 16 (S), 12 (I) 0.3
Vancomycin Staphylococcus sp. ≥15 127 127 0 0 0
a

Number of isolates susceptible or intermediate by both caliper and Sirscan. 

b

Number of isolates resistant by both caliper and Sirscan. 

c

Number of isolates susceptible or intermediate by caliper and resistant by Sirscan. 

d

Number of isolates resistant by caliper and susceptible or intermediate by Sirscan. 

e

S, sensitive; I, intermediate; R, resistant. 

f

(Number of Rc/SIs isolates) − (number of intermediate isolates)/number of isolates tested × 100.