TABLE 3.
Characteristics of SARS‐CoV‐2 (+) Kawasaki‐like systemic disease patients with oral mucosa findings
| Reference | Type of KD | Sex | Age | Systemic manifestions | Skin | Oral lesions | Onset | Hospitalization | Treatment of oral lesions |
|---|---|---|---|---|---|---|---|---|---|
| Akca et al. | IC | M | 7 | Fever, respiratory symptoms | Yes | Erosive hyperemia of oral mucosa | N/A | + | IVIG, azithromycin, hydroxochloroquine, ritonavir, lopinavir, tocilizumab, mesenchymal stem cell treatment |
| Alnashri et al. | KL‐MISC | M | 16 | Fever | Yes | Fissured lips | N/A | + | IVIG, tocilizumab |
| Bahrami et al. | KL‐MISC | F | 5 | Fever | Yes | Swelling and congestion of lips | After SS | + | IVIG, acetylsalicylic acid |
| Balasubramanian et al. | KL‐MISC | M | 8 | Fever, respiratory symptoms | Yes | Cracked lips, strawberry tongue | After SS | + | IVIG, aspirin, tocilizumab |
| Bhaswati et al. | C‐KD | M | 4 months | Fever | Yes | Red lips, red congested throat | N/A | + | Aspirin, IVIG |
| Blondiaux et al. | KL‐MISC | F | 8 | Fever | Yes | Cheilitis | With SS | + | IVIG, prednisolone, aspirin |
| Blondiaux et al. | KL‐MISC | F | 6 | Fever | Yes | Cheilitis | With SS | + | IVIG, prednisolone, aspirin |
| Chérif et al. | C‐KD | F | 35 | Fever, respiratory symptoms, hypogeusia | Yes | Chapped lips, with ulceration above the upper lip, lingual enanthema characterized by a reddish and swollen tongue | After SS | Hydroxychloroquine, azithromycin, cefuroxime | |
| Chiotos et al. | KL‐MISC | M | 12 | Fever, respiratory symptoms | N/A | Fissured lips | N/A | + | Methylprednisolone, IVIG |
| Chiotos et al. | KL‐MISC | F | 9 | Fever | No | Fissured lips, strawberry tongue | After SS | + | IVIG, methylprednisolone, aspirin |
| Chiotos et al. | KL‐MISC | F | 5 | Fever | Yes | Fissured lips | With SS | + | IVIG, methylprednisolone, anakinra |
| Chiu et al. | KL‐MISC | M | 10 | Fever | Yes | Cracked lips | After SS | + | Ibuprofen, dopamine |
| De Paulis et al. | KL‐MISC | F | 4 | Fever, respiratory symptoms | Yes | Cracked lips | After SS | + | Acyclovir, antibiotics, dobutamine, IVIG |
| Haena et al. | C+MIS‐C | M | 11 | Fever | Yes | Cracked lips, strawberry tongue | After SS | + | Aspirin, IVIG |
| Jones et al. | C‐KD | F | 6 months | Fever | Yes | Dry, cracked lips, prominent tongue papilla | After SS | + | IVIG, acetylsalicylic acid |
| Lidder et al. | IC | M | 45 | Fever, respiratory symptoms | Yes | Cheilitis, cracked lips | N/A | + | IVIG, tocilizumab, triamcinolone |
| Ng et al. | C+MIS‐C | M | 17 | Fever, respiratory symptoms | Yes | Cracked lips | N/A | + | IVIG, aspirin, ceftriaxone, clindamycin |
| Peterson et al. | C‐KD | F | 2 | Fever | Yes | Dry, cracked lips, strawberry tongue | After SS | + | IVIG, acetylsalicylic acid |
| Rafiei Tabatabaei S et al. | C‐KD | M | 11 | Fever, diarrhea, respiratory symptoms | Yes | Strawberry tongue | After SS | Yes | IVIG, ASA |
| Renganathan et al. | KL‐MISC | M | 10 | Fever, headache, irritability, disoriented speech | Yes | Dry cracked lips | N/A | + | IVIG, methylprednisolone |
| Rivera‐Figueroa et al. | IC | M | 5 | Fever | No | Dry, cracked, erythematous lips | N/A | + | IVIG, diphenhydramine, methylprednisolone, aspirin |
| Shaigany et al. | KL‐MISC | M | 45 | Fever, respiratory symptoms | Yes | Cracked lips | After SS | + | Heparin, IVIG, tocilizumab |
| Sokolovsky et al. | C‐KD | F | 36 | Fever, respiratory symptoms | Yes | Cracked lips | After SS | + | Aspirin, IVIG, methylprednisolone |
| Spencer et al. | IC | M | 11 | Fever, respiratory symptoms | Yes | Red, swollen lips | After SS | + | IVIG, corticosteroids |
| Spencer et al. | KL‐MISC | F | 7 | Fever, respiratory symptoms | Yes | Cracked lip, strawberry tongue | N/A | + | Corticosteroids. |
| Waltuch et al. | IC | M | 13 | Fever, respiratory symptoms | Yes | Erythematous tongue and oropharynx | After SS | + | Enoxaparin, antibiotics, IVIG, tocilizumab, anakinra |
| Waltuch et al. | IC | M | 5 | Fever, respiratory symptoms | Yes | Dry, cracked lip, mildly erythematous posterior oropharynx | N/A | + | Ceftriaxone, clindamycin, enoxaparin, IVIG, tocilizumab |