TABLE 5.
Characteristics of the patients with miscellaneous lesions
| Reference | Sex | Age | Systemic manifestions | Skin lesions | Oral lesions | Location/type | Onset | Hospitalization | Treatment of oral lesions |
|---|---|---|---|---|---|---|---|---|---|
| Ciccarese et al. | F | 19 | Fever, respiratory symptoms, hyposmia | Yes | Erosions, ulcers, blood crust, petechial enanthema | Overlap (ulcer, maculopapular enanthema) | After S | + | I.V. immune globulins, methylprednisolone |
| Cruz Tapia et al. | F | 51 | Fever | No | Macule (12 mm), papule‐plaque (8 mm) | Maculopapular enanthema | N/A | + | Dexamethasone, azithromycin, indomethacin |
| Cruz Tapia et al. | M | 42 | Fever, dysgeusia | No | Macules (3–4 mm), mucositis | Maculopapular enanthema |
After S Persistant after resolution |
N/A | Clorhexidine 0.12%, topical mometasone |
| Cruz Tapia et al. | F | 41 |
Fever, hyposmia, Myalgia, dysphagia |
No | Angina bullosa‐like hemorrhagic lesion (6 mm) on palate | Bullous | After S | − | N/A |
| Cruz Tapia et al. | F | 55 | Fever, headache, nasal congestion | No |
Purple bulla (8 mm) On hard palate |
Bullous | After S | − | N/A |
| Demirbaş et al. | F | 37 | Respiratory symptoms | Yes | Ulcers on lower lip tongue palate | Erythema multiforme |
After S 5th day of treatment |
+ | Methylprednisolone, anesthetic, and antiseptic mouthwashes |
| Holcomb et al. | M | 17 | Anosmia, ageusia | Yes | Mucositis, shallow erosions | Erythema multiforme | Without SS | − | Betamethasone, dexamethasone solution, viscous lidocaine, acetaminophen, ibuprofen |
| Kahraman et al. | M | 51 | Sore throat, fever, fatigue, dry cough, inability to taste or smell | No | Erythemathous surface in the oropharynx and in the hard palate, petechiae in the midline and numerous pustular enanthema near the soft palate border (1–3 mm in diameter) | Generalized |
After S 10th day |
− | Clarithromycin 500 mg b.i.d. PO |
| Labé et al. | M | 6 | Asymptomatic | Yes | Erosive cheilitis, gingival erosion, thick hemorrhagic crust |
Generalized Erythema multiforme |
N/A | + | N/A |
| McGoldrick et al. | M | 53 | No | No | Tongue and mouth swelling | Nonspecific | Before SS | + | IV steroid |
| Rodriguez et al. | F | 43 | Fever, respiratory symptoms, anosmia, dysgeusia | N/A | Aphthous‐like ulcer, tongue depapillation | Overlap | After S | − | Triamcinolone acetonide 0.05% |
| Soares et al.a | F | 23 | Fever, respiratory symptoms | Yes | Intact vesicobullous lesions on the vermillion border and hemorrhagic crusts on the outer surface of the lip | Bullous | After SS | N/A | Systemic dexamethasone |
| Soares et al. | M | 42 | Fever, cough, shortness of breath | Petechia‐like small vesiculobullous lesions | Ulcer, maculopapular enanthema | Overlap (ulcer, maculopapular enanthema) | After S | N/A | Dexamethasone, dipyrone |
| Tomo et al. | F | 37 | Fever, asthenia, dysgeusia, anosmia | No | Mucositis, diffuse bilateral erythema, petechia, depapillation of tongue | Generalized |
After S 9th day |
− |
Chlorhexidine 0.12% mouthwash Dexamethasone, metimazole |