FIGURE 2.
SARS-CoV-2–specific antibodies and T cells after priming stratified according to vector and mRNA vaccines. (A) Levels of SARS-CoV-2–specific IgG and neutralizing antibodies, as well as levels of SARS-CoV-2–specific (B) and SEB-reactive (C) CD4 and CD8 T cells after priming with vector or mRNA vaccines were compared among controls (open symbols) or among solid organ transplant recipients (SOT, filled symbols). Individuals who received the mRNA-1273 vaccine are indicated by triangles (5 controls, 1 SOT). Bars represent medians with interquartile ranges. Differences between the groups were calculated using Mann–Whitney test. Dotted lines in (A) indicate limits for IgG and neutralizing antibodies, including negative, intermediate and positive results, respectively as per manufacturer’s instructions. In (B) and (C) dotted lines indicate detection limits (DL) for SARS-CoV-2–specific and SEB-reactive CD4 and CD8 T cells. IFN, interferon