FIGURE 2.

Asymptomatic participants exhibit reduced SARS‐CoV‐2‐specific T‐cell functionality. (A) IFN‐γ and IL‐2 T‐cell responses amongst thirteen symptomatic and eleven asymptomatic SARS‐CoV‐2‐infected donors are shown for each individual. IFN‐γ (B) and IL‐2 (C) release by T cells in response to the SARS‐CoV‐2 S‐/NP‐/M‐combined peptide pool was measured in the symptomatic, asymptomatic and naïve donors (n = 76). P values resulting from Mann–Whitney tests are shown (**p < 0·01). The proportion of symptomatic, asymptomatic and naïve participants mounting dual IFN‐γ⁺/IL‐2⁺, single IFN‐γ or IL‐2⁺ or no measurable T‐cell response is shown (D)