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Ligand‐based NMR primary screening. Analyses of a 5‐fragment cocktail in the absence and in the presence of unlabeled 3CLp. a) 1D 1H and 1H Water‐LOGSY spectra. b) 1D 19F‐NMR of the same cocktail. Signals, annotated with an asterisk, correspond to the F04 fragment that is a direct binder. See Scheme S1 for other cocktails.
