Table 1.
Summary of SARS coronavirus 3CLpro inhibitor patents in chronological order up to 30 July 2021.
|
Patent number |
Applicant/Assignee |
Filing date (dd.mm.yyyy) |
Inhibitor type |
Fig. |
Ref. |
|---|---|---|---|---|---|
|
WO 2004/093860 |
Pfizer |
13.04.2004 |
peptidomimetic |
1 |
[20] |
|
WO 2004/101742 |
Cytovia |
06.05.2004 |
peptidomimetic |
2 |
[21] |
|
US 2006/0014821 |
Agouron Pharmaceuticals |
13.08.2004 |
peptidomimetic |
3 |
[22] |
|
WO 2005/041904 |
Fulcrum Pharmaceuticals |
01.11.2004 |
small molecule |
4 |
[23] |
|
WO 2005/066123 |
Taigen Biotechnology |
28.12.2004 |
peptidomimetic |
5 |
[24] |
|
WO 2005/113580 |
Pfizer |
09.05.2005 |
peptidomimetic |
6 |
[25] |
|
US 2006/0019967 |
National Health Research Institutes, Taiwan |
20.07.2005 |
small molecule |
7 |
[26] |
|
WO 2006/042478 |
Tsinghua University, Shanghai Institute of Organic Chemistry |
24.10.2005 |
peptidomimetic |
8 |
[27] |
|
CN 1965833 A |
Peking University |
18.11.2005 |
small molecule |
9 |
[28] |
|
WO 2006/061714 |
Pfizer |
06.12.2005 |
peptidomimetic |
10 |
[29] |
|
WO 2006/095624 |
Tokyo Medical and Dental University, RIKEN |
01.03.2006 |
small molecule |
11 |
[30] |
|
WO 2007/075145 |
Singapore Polytechnic, Shanghai Institute of Materia Medica |
15.12.2006 |
small molecule |
12 |
[31] |
|
CN 103159665B |
Tianjin International Joint Academy of Biotechnology and Medicine |
09.12.2011 |
small molecule |
13 |
[32] |
|
WO 2013/049382 |
Kansas State University, Ohio State University, Wichita State University |
27.09.2012 |
peptidomimetic |
14 |
[33] |
|
KR 1020130002975 |
Chonnam National University |
20.12.2012 |
small molecule |
15 |
[34] |
|
WO 2013/166319 |
Kansas State University, Wichita State University |
02.05.2013 |
peptidomimetic |
16 |
[35] |
|
CN 106176728 A |
Institute of Microbiology, Chinese Academy of Sciences |
07.07.2016 |
small molecule |
17 |
[36] |
|
WO 2017/114509 |
Shanghai Institute of Materia Medica, University of Lübeck |
30.12.2016 |
peptidomimetic |
18 |
[37] |
|
US 2017/0313685 |
Purdue Research Foundation |
28.04.2017 |
small molecule |
19 |
[38] |
|
WO 2017/222935 |
Kansas State University, Wichita State University |
16.07.2017 |
peptidomimetic |
20 |
[39] |
|
CN 108785293 A |
Tianjin International Joint Academy of Biomedicine |
28.04.2017 |
small molecule |
21 |
[40] |
|
WO 2018/042343 |
GSK |
30.08.2017 |
peptidomimetic |
22 |
[41] |
|
WO 2020/030143 |
Shanghai Institute of Materia Medica, Fudan University |
09.08.2019 |
peptidomimetic |
23 |
[42] |
|
WO 2021/176369 |
Pfizer |
03.03.2021 |
peptidomimetic |
24 |
[43] |