TABLE 2.
Comparison of patients in relation with myalgia and headache
| Myalgia (+) (110) | Myalgia (−) (112) | p (myalgia±) | Headache (+) (109) | Headache (−) (113) | p′ (headache±) | |
|---|---|---|---|---|---|---|
| Age (years) (median [Q3‐Q1]) | 38 (47–30) | 44 (53–30) | 0.04 | 39 (30–49) | 41 (30–52) | NS |
| Female sex | 64 (58.2%) | 42 (37.5%) | 0.02 | 64(58.7%) | 42(37.1%) | 0.01 |
| Hospitalisation | 64 (58.2%) | 75 (67%) | NS | 65 (56.6%) | 74(65.5%) | NS |
| Hospitalisation in ICU | 2 (1.9%) | 1 (0.9%) | NS | 1 (0.9%) | 2(1.8%) | NS |
| Hospitalisation period (days) (median [Q3–Q1]) | 7(12–5) | 6(10–5) | NS | 8(12–6) | 6(10–5) | 0.01 |
| Asthenia | 37 (33.6%) | 25 (22.3%) | NS | 39 (35.8%) | 23 (20.4%) | 0.01 |
| Fever | 63 (57.3%) | 43(38.4%) | 0.05 | 62 (56.9%) | 44 (38.9%) | 0.07 |
| Cough | 63(57.3%) | 51(45.5%) | NS | 67 (61.5%) | 47 (41.6%) | 0.03 |
| Sore throat | 49(44.5%) | 32(28.6%) | 0.01 | 48 (44%) | 33 (29%) | 0.02 |
| Anosmia | 65(59.1%) | 43(38.4%) | 0.02 | 59 (54.1%) | 49 (43.4%) | 0.01 |
| Headache | 69(62.7%) | 40(35.7%) | <0.001 | – | – | – |
| Myalgia | – | – | – | 69 (63.3%) | 41 (36.3%) | <0.001 |
| Arthralgia | 26(23.6%) | 4(3.6%) | <0.001 | 21 (19.3%) | 9 (8%) | 0.02 |
| Neuropathic pain | 35(31.8%) | 20(17.9%) | 0.012 | 43 (39.4%) | 12 (10.6%) | <0.001 |
| Comorbid disease | 31(28.2%) | 41(36.6%) | NS | 37 (33.9%) | 35 (31%) | NS |
| Smoking | 17(15.7%) | 19(17.4%) | NS | 14 (12.8%) | 22 (20.4%) | NS |
| Immuncompromised states | 4(3.8%) | 5(4.5%) | NS | 4 (3.7%) | 5(4.6%) | NS |
| Pneumonia | 49(45.4%) | 55(50.0%) | NS | 56 (51.9%) | 48 (43.6%) | NS |
| Laboratory findings median (Q3–Q1) | ||||||
| Leukocyte value at admission(K/µl) | 6190.0 (8002.5–4817.0) | 6855.0 (8530.0–5390.0) | NS | 6200.0 (8470.0–4990.0) | 6890.0 (8375.0–4920.0) | NS |
| Worst leukocyte value(K/µl) | 7205.0 (9262.5–5705.0) | 7630.0 (9090.0–6227.5) | NS | 7380.0 (9120.0–5830.0) | 7480.0 (9230.0–6027.0) | NS |
| Lymphocyte value at admission(K/µl) | 1746.5 (2307.3–1085.5) | 1864.0 (2605.5–1219.8) | NS | 1723.0 (6310.0–1130.0) | 1880.0 (7020.0–100.0) | NS |
| Worst lymphocyte value(K/µl) | 1370.5 (1940.8–950.0) | 1631.0 (2317.0–1086.3) | 0.04 | 1379.0 (2029.0–990.0) | 1606.0 (2295.0–1021.0) | NS |
| Ferritin level (µg/L) | 68.8 (150.2–25.3) | 125.6 (226.0–42.0) | 0.006 | 53.8 (157.8–21.6) | 123.0 (203.5–62.5) | 0.01 |
| Worst ferritin level (µg/L) | 90.0 (192.2–35.0) | 142.0 (296.0–56.1) | NS | 88.0 (233.9–31.5) | 139.6 (256.3–62.5) | 0.02 |
| CRP level at admission (mg/L) | 2.4 (7.1–2.0) | 3.7 (16.8–2) | NS | 2.5 (8.8–2.0) | 3.4 (13.3–2.0) | NS |
| Worst CRP level (mg/L) | 4.2 (18.0–2.0) | 5.1 (37.8–2.0) | NS | 5.2 (26.8–2.0) | 4.2 (20.0–2.0) | NS |
| CK at admission (U/L) | 69.0 (99.0–48.5) | 72.5 (99.3–51.8) | NS | 72.0 (95.5–49.0) | 71.5 (100.3–52.0) | NS |
| Worst CK value (U/L) | 75.0 (116.5–52.0) | 79.5 (112–52.8) | NS | 76.0 (112.0–51.0) | 80.0 (116.0–53.0) | NS |
| D‐dimer (mg/ml) | 0.3 (0.6–0.2) | 0.3 (0.6–0.2) | NS | 0.3 (0.6–0.2) | 0.3 (0.6–0.2) | NS |
| Worst D‐dimer value (mg/ml) | 0.4 (0.7–0.3) | 0.4 (0.3–0.8) | NS | 0.5 (0.8–0.3) | 0.4 (0.7–0.3) | NS |
| Procalcitonin (ng/ml) | 0.1 (0.1–0.0) | 0.1(0.2–0.1) | 0.027 | 0.1 (0.1–0.1) | 0.02 (0.1–0.1) | NS |
| Worst procalcitonin(ng/ml) | 0.1 (0.1–0.0) | 0.1(0.1–0.0) | NS | 0.1 (0.1–0.1) | 0.1(0.1–0.1) | NS |
| LDH value (U/L) | 193.0 (234.0–163.0) | 215.0 (271.5–184.0) | NS | 204.5 (267.5–171.3) | 198.0 (241.0–167.3) | NS |
| Worst LDH value (U/L) | 209.0 (258.0–179.0) | 227.0 (273.0–191.0) | NS | 227.5 (269.5–186.8) | 213.0 (263.8–179.0) | NS |
| AST value (U/L) | 20.0 (26.3–18.0) | 21.0 (26.0–17.0) | NS | 21.0 (27.0–17.0) | 21.0 (26.0–18.0) | NS |
| Worst AST value (U/L) | 24.0 (35.3– 20.0) | 24.0 (37.5–19.0) | NS | 25.0 (37.0–20.0) | 24.0 (36.0–19.0) | NS |
| ALT value (U/L) | 21.0 (29.3–16.0) | 20.0 (30.5–15.0) | NS | 20.0 (29.0–15.0) | 21.0 (33.0–15.3) | NS |
| Worst ALT value (U/L) | 25.0 (46.0–17.8) | 27.0 (51.5–16.5) | NS | 29.0 (46.0–19.0) | 24.5 (52.0–16.3) | NS |
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK, creatinine kinase; CRP, c‐reactive protein; LDH, lactate dehydrogenase; Q1, first quartile; Q3, third quartile. Please note that interquartile range is IQR = Q3‐Q1.
Bold indicates statistical significance.