TABLE 1.
The amino terminus of human MondoA regulates its subcellular localizationa
| Coexpressed proteins | % Nuc | % Nuc = cyto | % Cyto |
|---|---|---|---|
| hMondoA | 0 | 0 | 100 |
| Mlx | 4 ± 1.4 | 6 ± 1.4 | 90 ± 2.8 |
| ΔN445hMondoA | 100 ± .4 | 0 | 0 |
| Mlx | 100 ± 3 | 0 | 0 |
| ΔN322hMondoA | 100 | 0 | 0 |
| Mlx | 98.0 ± 17.3 | 2 ± .01 | 0 |
| ΔN224hMondoA | 21.7 ± 2.7 | 68.8 ± 13 | 9.5 ± 6.7 |
| Mlx | 53.2 ± 6.3 | 42.1 ± 1.2 | 4.8 ± 3.4 |
a
Percentages are given for the different staining patterns for Mlx and Mondo. Cells were transfected with the indicated combinations of expression plasmids, and the subcellular localization was scored in cells that expressed both proteins. Nuc, exclusively nuclear staining; Cyto, exclusively cytoplasmic staining; Nuc = Cyto, equivalent nuclear and cytoplasmic staining; hMondoA, human MondoA.