Fig. 1.
Glycyrrhizin (A; chemical structure) regulates the production of pro-inflammatory MIF (B) and homeostatic SDF-1/CXCL12 (C) chemokines for OCPs in the particle-induced calvarial lesions of aged mice. Calvarial tissues were sampled from wild type aged (twenty-four-month-old) mice and then were evaluated by an ELISA assay. *p < 0.05, **p < 0.01; ***p < 0.001. GLY – Glycyrrhizin.