Table 4.

Univariate and multivariable regression results for association between NLR and all factors included in 5 or more survey years.

		Univariate				Multivariable

Factor	Level	N (level) ¹	Coefficient		p-val	N (level) ¹	Coefficient		p-val

Sex	Male	23,206		Ref		10,704		Ref
	Female	24,817	−0.03		0.008	9,533	−0.13		4.13E-12

Age	<60	33,039		Ref		13,685		Ref
	≥60	14,984	0.28		<2E-16	6,552	0.12		7.05E-07
	Continuous	48,023	0.0066		<2E-16	20,237

Race	Non-Hispanic White	21,254		Ref		9,251		Ref
	Non-Hispanic Black	9,928	−0.59		<2E-16	4,066	−0.53		<2E-16
	Mexican American	9,138	−0.20		<2E-16	3,019	−0.10		3.42E-04
	Other Hispanic	3,847	−0.28		<2E-16	2,089	−0.16		2.34E-07
	Other Race	3,856	−0.31		<2E-16	1,812	−0.21		2.68E-11

Education Level	Less than 12th grade	12,430		Ref		4,674		Ref
	High school/GED or equivalent	22,657	0.009		0.51	10,707	0.05		0.02
	College graduate or above	9,452	−0.003		0.84	4,843	0.08		0.01

Marital Status	Married	23,641		Ref		10,419		Ref
	Widowed	3,856	0.27		<2E-16	1,391	0.19		9.99E-07
	Divorced	4,465	−0.005		0.8	2,355	0.03		0.28
	Separated	1,468	−0.04		0.23	683	0.12		0.02
	Never married	9,432	−0.10		3.64E-11	3,691	0.05		0.04
	Living with partner	3,323	−0.12		1.06E-07	1,692	−0.05		0.17

People in Household	1	6,391		Ref		2,900		Ref
	2	14,156	−0.06		2.00E-03	6,261	0.01		0.67
	3	8,683	−0.17		<2E-16	3,621	0.01		0.68
	4	7,857	−0.21		<2E-16	3,284	0.04		0.33
	5	5,240	−0.23		<2E-16	2,065	0.02		0.60
	6	2,647	−0.21		5.59E-13	1,051	0.06		0.24
	7+	3,049	−0.27		<2E-16	1,055	−0.07		0.17
	Continuous	48,023	−0.05		<2E-16	20,237

Income	< $20,000	10,662		Ref		4,015		Ref
	$20,000 to $44,999	13,860	−0.05		0.001	5,701	0.004		0.89
	$45,000 to $74,999	8,762	−0.08		5.67E-06	3,855	−0.04		0.17
	≥ $75,000	10,327	−0.13		9.27E-15	5,295	−0.06		0.05

Health Insurance	Yes	37,185		Ref		15,746		Ref
	No	10,601	−0.15		<2E-16	4,474	−0.03		0.18

Ever Smoker	Yes	20,596		Ref		10,218		Ref
	No	24,494	−0.14		<2E-16	10,002	−0.06		0.0007

Alcohol use I (drinking days per year)	None	7,988		Ref		4,306		Ref
Alcohol use I (drinking days per year)	≤ 10	7,995	−0.16		1.57E-15	4,522	−0.09		0.001
	> 10 and ≤ 50	7,209	−0.18		<2E-16	4,226	−0.05		0.09
	> 50 and ≤ 100	3,838	−0.19		3.41E-15	2,243	−0.08		0.009
	> 100	8,263	−0.11		2.65E-08	4,915	−0.02		0.44
	Continuous	35,293	−0.02		1.72E-06	20,212

BMI	≤ 18.5	914		Ref		307		Ref
	> 18.5 and ≤ 25	14,285	−0.01		0.77	5,558	−0.10		0.14
	> 25 and ≤ 30	15,676	−0.02		0.66	6,740	−0.17		0.02
	> 30	16,300	−0.02	0.57		7,632	−0.16		0.02
	Continuous	47,175	−0.09		0.4	20,237

Physical Activity	None	14,627		Ref		10,280		Ref
	Moderate only	7,136	−0.08		1.67E-05	5,360	−0.08		0.0002
	Vigorous only	2,257	−0.26		<2E-16	1,560	−0.13		0.0002
	Moderate and vigorous	4,001	−0.23		<2E-16	3,030	−0.13		8.11E-07

Time sitting/reclining	≤ 1 hour	4,371		Ref		2,977		Ref
	> 1 hour and ≤ 2 hours	12,820	0.08		9.47E-05	9,412	0.04		0.12
	> 2 hours and ≤ 4 hours	9,789	0.15		5.51E-12	7,138	0.11		3.76E-05
	> 4 hours	903	0.16		0.0003	648	0.05		0.4
	Continuous	27,883	0.07		5.88E-13	20,175

Arthritis	Yes	11,739		Ref		5,470		Ref
	No	32,775	−0.19		<2E-16	14,728	−0.02		0.43

Heart condition	Yes	4,925		Ref		2,165		Ref
	No	39,611	−0.43		<2E-16	18,053	−0.22		5.82E-13

Emphysema	Yes	910		Ref		473		Ref
	No	43,630	−0.72		<2E-16	19,744	−0.33		1.59E-08

Cancer	Yes	3,997		Ref		1,970		Ref
	No	40,553	−0.37		<2E-16	18,250	−0.15		8.95E-07

Diabetes	Yes	5,252		Ref		2,491		Ref
	No	41,876	−0.20		<2E-16	17,268	−0.16		2.33E-08
	Borderline	862	−0.13		0.003	465	−0.17		0.00473

Hypertension	Yes	15,457		Ref		7,268		Ref
	No	32,330	−0.17		<2E-16	12,946	−0.07		0.00129

Univariate models include all available participants. Lower N values in multivariable model reflect restriction to only participants with complete data for all included variables. Note that participants reporting “refused/don#x2019;t know#x201D; are excluded from this table for brevity, and thus slight variations from these participant totals may be observed.