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. Author manuscript; available in PMC: 2021 Dec 8.
Published in final edited form as: Ann Epidemiol. 2019 Aug 1;38:11–21.e6. doi: 10.1016/j.annepidem.2019.07.015

Table 5.

Associations between demographic and lifestyle factors (sex, age, ever-smoker status, alcohol use, BMI and physical activity) and NLR within independent subgroups of the participant population classified by race/ethnicity, age and sex. A. Participants with comorbidities. B. Participants without comorbidities.

Table 5a. Subjects with comorbidity
Non-Hispanic white Non-Hispanic black Hispanic
Factor Level Age Sex Age Sex Age Sex
<60 >60 M F <60 >60 M F <60 >60 M F
Sex M Ref Ref Ref
F −0.08 −0.50 *** −0.18 ** −0.30 ** −0.13 −0.38 **
Age <60 Ref Ref Ref
≥60 0.39 *** 0.01 0.005 0.05 0.26 * −0.11
Ever Smoker Yes Ref Ref Ref Ref Ref Ref
No −0.05 −0.15 * −0.12 −0.09 0.04 0.01 0.007 0.08 −0.04 0.01 −0.09 0.05
Alcohol use 1 (drinking days per year) None Ref Ref Ref Ref Ref Ref
≤ 10 −0.06 0.007 0.14 −0.16 * −0.02 −0.10 0.02 −0.16 −0.07 −0.17 −0.17 −0.09
> 10 and ≤ 50 −0.03 0.04 0.14 −0.12 −0.003 −0.07 −0.04 −0.09 0.05 −0.21 −0.22 0.01
> 50 and ≤ 100 −0.08 −0.008 0.05 −0.10 −0.04 −0.24 −0.13 −0.19 −0.02 0.04 0.04 −0.05
> 100 −0.09 −0.10 −0.01 −0.15 0.09 −0.05 0.06 −0.07 0.06 −0.02 −0.04 0.20
BMI ≤ 25 Ref Ref Ref Ref Ref Ref
>25 0.03 −0.27 *** −0.13 ** 0.01 −0.01 −0.36 *** −0.11 −0.13 −0.02 −0.003 −0.01 −0.03
Physical Activity None Ref Ref Ref Ref Ref Ref
Moderate only −0.10 −0.31 *** −0.25 *** −0.18 ** 0.03 −0.14 −0.10 −0.02 −0.02 0.04 −0.04 0.05
Vigorous only −0.31 ** −0.15 −0.25 −0.28 −0.14 −0.07 −0.10 −0.10 −0.26 * −0.13 −0.23 −0.29
Moderate and vigorous −0.24 ** −0.24 −0.21 * −0.28 ** −0.10 −0.12 −0.15 0.02 −0.20 * −0.53 * −0.30 −0.29 *
Table 5b. Subjects without comorbidity
Non-Hispanic White Non-Hispanic Black Hispanic
Factor Level Age Sex Age Sex Age Sex
<60 >60 M F <60 >60 M F <60 >60 M F
Sex M Ref Ref Ref
F 0.04 −0.46 *** 0.08 −0.23 0.11 ** −0.19
Age <60 Ref Ref Ref
≥60 0.34 *** −0.15 0.14 −0.18 0.18 * −0.22
Ever Smoker Yes Ref Ref Ref Ref Ref Ref
No −0.03 −0.10 −0.007 −0.07 −0.08 −0.09 −0.14 0.007 0.006 −0.27 −0.04 −0.71
Alcohol use 1 (drinking days per year) None Ref Ref Ref Ref Ref Ref
≤ 10 −0.01 0.004 −0.06 0.06 −0.05 −0.10 −0.07 −0.14 −0.19 ** −0.09 −0.18 * −0.17 *
> 10 and ≤ 50 −0.03 −0.08 −0.08 0.05 0.15 −0.08 0.19 −0.02 −0.11 −0.02 −0.08 −0.11
> 50 and ≤ 100 −0.06 −0.05 −0.12 0.03 −0.02 −0.24 −0.01 −0.07 −0.08 −0.10 −0.13 0.06
> 100 0.05 −0.006 −0.01 0.10 0.13 −0.10 0.12 −0.006 −0.0009 0.23 0.08 −0.08
BMI ≤ 25 Ref Ref Ref Ref Ref Ref
>25 0.04 −0.29 * −0.03 0.04 −0.02 0.11 −0.03 0.02 0.02 −0.20 −0.02 0.02
Physical Activity None Ref Ref Ref Ref Ref Ref
Moderate only −0.03 −0.03 −0.03 −0.02 −0.03 −0.08 −0.06 −0.05 −0.01 0.14 −0.05 0.02
Vigorous only −0.16 ** −0.13 −0.17 * −0.14 0.16 −0.65 0.15 0.19 −0.009 −0.11 −0.005 −0.02
Moderate and vigorous −0.12 * −0.06 0.009 −0.24 *** 0.04 −0.14 0.03 0.02 −0.07 0.10 −0.08 −0.02

Results represent b coefficient and p value from a multivariable regression model that included all factors included in the multivariable model of Table 4 and also presence of comorbidities (arthritis, heart disease, diabetes, cancer, emphysema and hypertension).

***

represents p<0.001

**

represents p<0.01, and

*

represents p<0.05.