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. 2021 Dec 8;21:188. doi: 10.1186/s12880-021-00713-1

Table 2.

Relationships between lymphoscintigraphic findings and volume change

Qualitative lymphoscintigraphic indicators Volume difference ratio at 3 months Volume difference ratio at 1 year
N Mean rank p-value N Mean rank p-value
Inguinal LN uptake Absent 7 8.71 N-S 7 9.71 N-S
Present 10 9.20 10 8.50
Main lymphatic vessel Absent 13 10.23 N-S 13 9.46 N-S
Present 4 5.00 4 7.50
Collateral vessel Absent 15 9.13 N-S 15 9.60 N-S
Present 2 8.00 2 4.50
Dermal backflow (Pattern 1) Absent 5 6.80 N-S 5 5.60 N-S
Present 12 9.92 12 10.42
Dermal backflow (Pattern 2) Absent OR distal only 12 8.08 N-S 12 8.42 N-S
Proximal only OR whole lower limb 5 11.20 5 10.40
Dermal backflow (Pattern 3) Absent OR proximal only 7 6.71 N-S 7 5.29 0.010*
Distal only OR whole lower limb 10 10.60 10 11.60
Dermal backflow (Pattern 4) Absent OR distal only OR proximal only 14 7.86 0.047* 14 7.86 0.047*
Whole lower limb 3 14.33 3 14.33
Quantitative lymphoscintigraphic indicators Volume difference ratio at 3 months Volume difference ratio at 1 year
Correlation coefficient (Spearman’s rho) p value Correlation coefficient (Spearman’s rho) p-value
1 h LN uptake ratio − 0.007 N-S 0.020 N-S
1 h Extremity uptake ratio 0.431 N-S 0.456 N-S
1 h Injection site clearance ratio − 0.336 N-S -0.130 N-S
2 h LN uptake ratio 0.007 N-S 0.044 N-S
2 h Extremity uptake ratio 0.574 0.016* 0.723 0.001*
2 h Injection site clearance ratio − 0.034 N-S 0.066 N-S

*Statistically significant; N-S, not statistically significant