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. 2021 Dec 8;19:311. doi: 10.1186/s12916-021-02173-4

Table 3.

Effect of P-gp inducer sodium ferulate on maternal weight gain rate, fetal body, and placental weights

Group Maternal weight gain rate (%) Fetal body weight (g) Placental weight (g)
Female Male Female Male
Control 52.0±1.5 1.100±0.024 1.100±0.026 0.085 ± 0.0037 0.086 ± 0.0031
Caffeine 40.0±1.7** 0.850±0.026 * 0.870±0.030 * 0.072 ± 0.003 ** 0.074 ± 0.0025 **
Sodium ferulate 52.0±1.5 1.100±0.063 1.200±0.062 0.090±0.0031 0.095 ± 0.0039
Caffeine + sodium ferulate 47.0±2.8# 0.990 ±0.062 ## 1.000±0.053 ## 0.088±0.0029 # 0.093 ± 0.0028 #

*P<0.05, **P<0.01 vs. control; #P<0.05, ##P<0.01 vs. caffeine