Table 2.

HDACIs classification

Class	Member	Target (HDAC specifity)
Short-chain fatty acids	Valproic acid, Sodium butyrate	I, IIa I, II
Hydroxamic acids	TSA SAHA CHR-3996 Belinostat Givinostat Panobinostat Resminostat Quisinostat Abexinostat Rocilinostat Practinostat Tubacin	Pan Pan I Pan Pan Pan Pan Pan Pan II I, II, IV IIb
Cyclic tetrapeptides	Romidepsin Apicidin	I I
Benzamides	4SC202 MS-275 Mocetinostat MGCD0103 Entinostat Tacedinaline CI-994	I I I, IV I I I I
Sirtuins inhibitors	EX-527 Cambinol Sirtinol Nicotinamide	SIRT 1 SIRT 1, and 2 SIRT 1, and 2 3 (all classes)