Table 3.

The target of HDACIs in HCC

Class	Member	Target HDAC class	Cell line	Reference
short-chain fatty acids	Valproic acid (VPA),	class I, IIa	hepatocellular carcinoma HepG 2 cells	A
Aliphatic fatty acid	sodium butyrate	class I, IIa	SMMC-7721 and HepG2 cells	B
Aliphatic fatty acid	sodium butyrate	class I, IIa	HCC SMMC-7721 and HepG2 cells	C
Hydroxamic acid	TSA	Pan	HCC SMMC-7721 and HepG2 cells	C
Hydroxamic acid	trichostatinA (TSA)	Pan	Hep3B,HepG2, Hep3B	D
Hydroxamates	(SAHA)	Pan	Bel-7402, HepG2	E, F