Table 6.
Results of parameters obtained after fitting data release of QTF-loaded SEDDS to different kinetic models
| Kinetic model | R2adj | AIC | Other parameters | Results |
|---|---|---|---|---|
| Zero-order | -21.8729 | 55.9229 | k | 2.263 |
| First-order | 0.9850 | 10.6613 | k | 0.151 |
| Higuchi | -5.3309 | 48.0458 | k | 15.806 |
| Krosmeyer-peppas | 0.7160 | 30.3263 | k | 62.469 |
| n | 0.124 | |||
| Weibull | 0.9940 | 7.2557 | T | -8.582 |
| β | 1.41 | |||
| Td | 6.799 | |||
| Hopfenberg | 0.9862 | 10.3832 | k | 0.011 |
| n | 1873.824 |
*R2adj indicated Adjusted coefficient of determination; AIC: Akaike information criteria; k: release rate constant; n: has a value of 1, 2, and 3 for a slab,
cylinder, and sphere, respectively; T: time; Td: the time required to dissolve 63,2% of the drug; and β: shape parameter.