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. 2021 Summer;20(3):381–398. doi: 10.22037/ijpr.2021.114785.15032

Table 6.

Results of parameters obtained after fitting data release of QTF-loaded SEDDS to different kinetic models

Kinetic model R2adj AIC Other parameters Results
Zero-order -21.8729 55.9229 k 2.263
First-order 0.9850 10.6613 k 0.151
Higuchi -5.3309 48.0458 k 15.806
Krosmeyer-peppas 0.7160 30.3263 k 62.469
n 0.124
Weibull 0.9940 7.2557 T -8.582
β 1.41
Td 6.799
Hopfenberg 0.9862 10.3832 k 0.011
n 1873.824

*R2adj indicated Adjusted coefficient of determination; AIC: Akaike information criteria; k: release rate constant; n: has a value of 1, 2, and 3 for a slab,

cylinder, and sphere, respectively; T: time; Td: the time required to dissolve 63,2% of the drug; and β: shape parameter.