Table 2.

Number of cases of side effects and proportion in total participants

		10 days		3 months		6 months		12 months		24 months		Total
		n （ % ）		n （ % ）		n （ % ）		n （ % ）		n （ % ）		n （ % ）
endless		0 (0%)		5 (2.37%)		6 (2.84%)		12 (5.69%)		16 (7.58%)		39 (18.48%)
prolonged		0 (0%)		2 (0.95%)		5 (2.37%)		9 (4.27%)		7 (3.31%)		23 (10.90%)
Increased volume		0 (0%)		3 (1.425)		4 (1.90%)		5 (2.37%)		5 (2.37%)		17 (8.06%)
decreased volume		0 (0%)		3 (1.42%)		9 (4.27%)		3 (1.42%)		4 (1.90%)		19 (0.90%)
amenorrhea		0 (0%)		4 (1.90%)		4 (1.90%)		4 (1.90%)		4 (1.90%)		16 (7.58%)
frequent		0 (0%)		4 (1.90%)		4 (1.90%)		4 (1.90%)		4 (1.90%)		16 (7.58%)
weight gain		0 (0%)		1 (0.47%)		1 (0.47%)		3 (1.42%)		4 (1.90%）		9 (4.27%)
Dizziness\ headache		2 (0.95%)		3 (1.42%)		4 (1.90%)		2 (0.95%)		2 (0.95%)		13 (6.12%)
acne		0 (0%)		1 (0.47%)		2 (0.94%)		1 (0.47%)		1 (0.47%)		4 (1.90%)
Low sexual desire		0 (0%)		1 (0.47%)		1 (0.47%)		0 (0%)		1 (0.47%)		3 (1.42%)
sleep quality drop		1 (0.47%)		1 (0.47%)		1 (0.47%)		1 (0.47%)		1 (0.47%)		5 (2.37%)
Upper lip hair increased		0 (0%)		1 (0.47%)		1 (0.47%)		1 (0.47%)		1 (0.47%)		4 (1.90%)
blood pressure decreased		0 (0%)		1 (0.47%)		1 (0.47%)		1 (0.47%)		1 (0.47%)		4 (1.90%)
ovarian cyst		0 (0%)		0 (0%)		0 (0%)		1 (0.47%)		0 (0%)		1 (0.47%)