Table 3.

Summary of studies on the fate of reverse migrated neutrophils.

Title	Model	Major finding	Ref.
Implication and fate of reverse-migrated neutrophils
Spatiotemporal photolabeling of neutrophil trafficking during inflammation in live zebrafish	In vivo: Zebrafish	Visualization of the origin and fate of neutrophils during induction and resolution of inflammation	(50)
Reverse-migrated neutrophils regulated by JAM-C are involved in acute pancreatitis-associated lung injury.	In vivo: Mouse	Neutrophils that are recruited to the pancreas may reverse migrate back into circulation and could potentially contribute to acute lung injury during acute pancreatitis	(52)
Microbe-dependent lymphatic migration of neutrophils modulates lymphocyte proliferation in lymph nodes.	In vivo: Mouse	Skin-egressing neutrophils migrate to the lymph nodes to augment lymphocyte proliferation in draining lymph nodes.	(53)
Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes	In vivo: Mouse	Neutrophils migrate to lymphoid tissue and can shuttle live microorganisms.	(55)