Table 4.
Summary of studies on neutrophil interaction with other immune cells.
| Cell type | Model | Major finding | Ref. |
|---|---|---|---|
| Neutrophil and other immune cells interaction | |||
| Neutrophil | Ex vivo: Microfluidic | Intracellular communication among neutrophils is driven by LTB4 | (66) |
| (73) | |||
| Monocytes | Ex vivo: Microfluidic | Monocytes promote neutrophil response in an LPS dependent manner | (86) |
| Neutrophils-pathogen interaction | |||
| Fungus | In vitro | Established chemoattractant gradients primed neutrophils to inhibit fungi growth. | (76) |
| Ex vivo: Microfluidic | Neutrophils exhibited an immune response to A. fumigatus via paracrine and autocrine signaling | (86) | |
| Bacterium | In vitro | Neutrophils exhibited an immune response to bacteria compared to LPS | (74) |
| Ex vivo: Microfluidic | The activation of endothelial cells by P. aeruginosa increased migration in neutrophils | (22) | |