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. 2021 Nov 24;12:781535. doi: 10.3389/fimmu.2021.781535

Table 4.

Summary of studies on neutrophil interaction with other immune cells.

Cell type Model Major finding Ref.
Neutrophil and other immune cells interaction
Neutrophil Ex vivo: Microfluidic Intracellular communication among neutrophils is driven by LTB4 (66)
(73)
Monocytes Ex vivo: Microfluidic Monocytes promote neutrophil response in an LPS dependent manner (86)
Neutrophils-pathogen interaction
Fungus In vitro Established chemoattractant gradients primed neutrophils to inhibit fungi growth. (76)
Ex vivo: Microfluidic Neutrophils exhibited an immune response to A. fumigatus via paracrine and autocrine signaling (86)
Bacterium In vitro Neutrophils exhibited an immune response to bacteria compared to LPS (74)
Ex vivo: Microfluidic The activation of endothelial cells by P. aeruginosa increased migration in neutrophils (22)