TABLE 2.
Numbers of ET12 (n = 27) isolates with concordant, discordant, and inconclusive identification by the IR Biotyper and MALDI-TOF MS with various typing models
| Classification (n = 27 isolates)a | ANN class call color code | No. (%) of isolates identified by: |
||||
|---|---|---|---|---|---|---|
| IR Biotyper withb: |
MALDI-TOF MS–ClinProTools with SVM at a cutoff ofc: |
|||||
| LDA | ANN | PCA | 80% | 70% | ||
| Concordant | Green | 22 (81.5) | 21 (77.8) | 16 (59.3) | 17 (63.0) | 21 (77.8) |
| Discordant | Red | 4 (14.8) | 5 (18.5) | 9 (37.5) | 2 (7.4) | 3 (11.1) |
| Inconclusive | Yellow | 1 (3.7) | 1 (3.7) | 2 (7.4) | 8 (29.6) | 3 (11.1) |
a
Only isolates used for all methods were included in the external validation set.
b
LDA, linear discriminant analysis; ANN, artificial neural network; PCA, principal-component analysis.
c
SVM, support vector machine.