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. 2021 Dec 8;9(3):e01928-21. doi: 10.1128/Spectrum.01928-21

TABLE 3.

Breakpoints used for drug susceptibility of testing rapidly growing mycobacteria by broth dilutiona

Antibiotic MIC (μg/mL)
Broth dilution range (μg/mL)
Susceptible Intermediate Resistant
Clarithromycin ≤2 4 ≥8 0.06–64
Azithromycin ≤2 4 ≥8 0.0664
Amikacin ≤16 32 ≥64 4128
Tobramycin ≤2 4 ≥8 0.516
Imipenem ≤4 8–16 ≥32 264
Meropenem ≤4 8–16 ≥32 264
Faropenem N/A N/A N/A 264
Levofloxacin ≤1 2 ≥4 132
Moxifloxacin ≤1 2 ≥4 0.258
Sitafloxacin N/A N/A N/A 0.258
Trimethoprim/sulfamethoxazole ≤38/2 N/A ≥76/4 4.8/0.25152/8
Doxycycline ≤1 2–4 ≥8 0.516
Linezolid ≤8 16 ≥32 132
Clofazimine N/A N/A N/A 0.062
a

MIC, minimum inhibitory concentration; N/A, not applicable.