TABLE 3.
Breakpoints used for drug susceptibility of testing rapidly growing mycobacteria by broth dilutiona
| Antibiotic | MIC (μg/mL) |
Broth dilution range (μg/mL) | ||
|---|---|---|---|---|
| Susceptible | Intermediate | Resistant | ||
| Clarithromycin | ≤2 | 4 | ≥8 | 0.06–64 |
| Azithromycin | ≤2 | 4 | ≥8 | 0.06–64 |
| Amikacin | ≤16 | 32 | ≥64 | 4–128 |
| Tobramycin | ≤2 | 4 | ≥8 | 0.5–16 |
| Imipenem | ≤4 | 8–16 | ≥32 | 2–64 |
| Meropenem | ≤4 | 8–16 | ≥32 | 2–64 |
| Faropenem | N/A | N/A | N/A | 2–64 |
| Levofloxacin | ≤1 | 2 | ≥4 | 1–32 |
| Moxifloxacin | ≤1 | 2 | ≥4 | 0.25–8 |
| Sitafloxacin | N/A | N/A | N/A | 0.25–8 |
| Trimethoprim/sulfamethoxazole | ≤38/2 | N/A | ≥76/4 | 4.8/0.25–152/8 |
| Doxycycline | ≤1 | 2–4 | ≥8 | 0.5–16 |
| Linezolid | ≤8 | 16 | ≥32 | 1–32 |
| Clofazimine | N/A | N/A | N/A | 0.06–2 |
MIC, minimum inhibitory concentration; N/A, not applicable.