TABLE 1.
Summary of prion seeding activity in mountain lion feces following oral exposure to CWD prions
| Fecal sample | CWD prion-spiked meal on day 0 | Days post-feeding | RT-QuIC resultsb |
|---|---|---|---|
| Expt 1 | |||
| Female | Yes | 3 | 10/12 |
| 5 | 0/8 | ||
| 6 | 0/12 | ||
| 7 | 0/8 | ||
| Male | No | 2 | 0/8 |
| 4 | 0/8 | ||
| 6 | 0/8 | ||
| 7 | 0/8 | ||
| Expt 2 | |||
| Female | No | 3 | 0/8 |
| 5a | 0/8 | ||
| 5b | 0/8 | ||
| 6 | 0/8 | ||
| Male | Yes | 3 | 12/12 |
| 5 | 0/8 | ||
| 6 | 2/12 | ||
| Natural feeding 1 | NAa | 2 | 7/8 |
| Natural feeding 2 | NA | 2 | 4/8 |
| Control lions (n = 5) | No | NA | 1/48 |
a
NA, not applicable; the lions in these experiments were allowed to feed freely on a CWD-infected carcass.
b
Number of positive RT-QuIC reactions over the total number of wells tested.