Table 3.
List of Genes that Showed Epigenomic and Transcriptomic Overlap Differences and Enriched Metacore Terms
| DNA methylation | Gene expression | ||||||
|---|---|---|---|---|---|---|---|
| Position (build GRCh37/hg19) | Gene annotated to DMRs | Transcript | P value | LFC | P value | LFC | Number metacore term |
| chr16: 4102293-4103533 | ADCY9 | Adenylate Cyclase 9 | 8.85–14 | −0.032 | .0059 | −0.42 | 4 |
| chr8:67088895-67091580 | CRH | Corticotrophin releasing hormone | 3.59–28 | 0.026 | .0006 | 1.13 | 4 |
| chr14:24834695-24839226 | NFATC4 | Nuclear factor of activated T cells 4 | 6.80–21 | 0.017 | .0007 | 1.12 | 3 |
| chr11:17497693-17498952 | ABCC8 | ATP binding cassette subfamily C member 8 | 9.23–22 | 0.011 | .0057 | −0.55 | 3 |
| chr6:34202568-34204646 | HMGA1 | High mobility group AT-Hook 1 | 2.47–20 | 0.023 | .0088 | 0.33 | 2 |
| chr17:4027290140275359 | KAT2A | Lysine acetyltransferase 2A | 3.80–18 | −0.011 | .0012 | −0.55 | 2 |
| chr1:16481715-16483658 | EPHA2 | EPH receptor 2 | 1.99–27 | 0.016 | .0092 | −0.36 | 2 |
| chr7:98475615-98477438 | TRRAP | Transformation/transcription Domain associated protein | 3.37–47 | −0.013 | .0082 | −0.39 | 1 |
| chr19:35818807-35820181 | CD22 | CD22 molecule | 5.89–36 | 0.056 | .0047 | −0.62 | 1 |
| chr16:49311483-49314257 | CBLN1 | Cerebellin 1 precursor | 9.80–19 | 0.029 | .0058 | 0.33 | 1 |
Abbreviations: Chr, chromosome; DMRs, differentially methylated regions; LFC, log fold change.