Male npy1r-cre mice received
unilateral PVN injections of a cre-dependent adeno-associated
virus (AAV), allowing for the selective expression of a fluorescent protein
(mCherry; left panel) in synaptosomes, which can be visualized in the cell
bodies, axon fibers, and synapses of NPY Y1R-containing neurons (middle panel).
Images show that 95% (19/20) of neurons that expressed mCherry (magenta) also
expressed mRNA for the NPY1R (green puncta; at least 3 per neuron), quantified
using RNAScope (right panel).