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. 2021 Nov 24;11:790422. doi: 10.3389/fcimb.2021.790422

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Copyright © 2021 Lu, Zhou, Wu, Fu, Yan, He, Sun, Ji and Shao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Procrustes analysis and Co-occurrence network analysis between virome and bacteriome in COVID-19. (A) Procrustes analysis of the correlation between viral and bacterial communities of COVID-19 patients. (B) Co-occurrence network analysis between virome and bacteriome. Each nodes represents virus and bacteria on family levels. Edges represented positive associations (red) and negative associations (green) between virus and bacteria. The cutoff of the Spearman correlation and p-value were set at 0.3 and 0.05, respectively.