Table 2.

Effects of feeding mannan oligosaccharides (MOS) and Lactobacillus mucosae (LM) on performance of weanling pigs challenged with Escherichia coli lipopolysaccharides (LPS)¹

	Treatment1					P-values
Item2	Control	MOS	LM	MOS+LM	SEM3	MOS	LM	MOS × LM
BW, kg
Day 0	5.89	5.88	5.89	5.87	0.18	0.927	0.991	0.980
Day 7	6.02	5.97	5.79	5.70	0.20	0.750	0.240	0.926
Day 14	7.82	7.85	7.88	7.69	0.34	0.813	0.889	0.767
Day 21	9.67	10.19	10.19	9.65	0.49	0.744	0.722	0.205
Day 35	18.32	18.14	18.82	17.96	1.16	0.655	0.892	0.768
Pre-LPS challenge
Day 0 to 7
ADG, g	17.98	13.09	-15.36	-24.41	20	0.737	0.105	0.920
ADFI, g	102.68	100.12	127.86	129.17	11	0.968	0.096	0.900
G:F, g/kg	—	—	—	—	—	—	—	—
Days 7 to 14
ADG, g	258.10	267.74	298.81	284.64	28	0.939	0.338	0.687
ADFI, g	306.49	303.69	325.71	328.10	24	0.993	0.376	0.915
G:F, g/kg	841.61	877.64	918.71	861.44	37	0.841	0.567	0.385
Days 0 to 14
ADG, g	138.04	140.41	141.72	130.12	16	0.780	0.841	0.672
ADFI, g	204.58	201.90	226.78	228.63	17	0.981	0.178	0.897
G:F, g/kg	668.34ab	686.96a	627.97ab	561.48b	36	0.523	0.042	0.265
Post-LPS challenge
Days 14 to 21
ADG, g	271.57	339.39	350.82	292.14	35	0.898	0.654	0.094
ADFI, g	440.83	502.59	487.37	482.90	38	0.460	0.727	0.395
G:F, g/kg	615.09ab	673.85ab	715.41a	599.76b	38	0.466	0.735	0.040
Days 21 to 28
ADG, g	571.79	541.79	573.87	523.27	29	0.196	0.785	0.733
ADFI, g	781.70	752.50	829.29	803.33	41	0.517	0.257	0.969
G:F, g/kg	731.40a	719.53a	693.78ab	651.50b	16	0.119	0.007	0.364
Days 28 to 35
ADG, g	648.04	589.88	626.67	649.58	34	0.619	0.588	0.262
ADFI, g	993.93ab	884.59b	1,029.29ab	1,039.70a	50	0.342	0.050	0.254
G:F, g/kg	650.71	665.42	612.12	625.82	22	0.525	0.097	0.982
Days 21 to 35
ADG, g	609.91	565.83	600.27	586.43	28	0.316	0.846	0.595
ADFI, g	887.81	818.54	929.28	921.52	42	0.382	0.114	0.482
G:F, g/kg	686.50ab	690.69a	648.55ab	636.80b	17	0.827	0.019	0.647
Days 0 to 35
ADG, g	355.29	348.33	363.51	349.05	18	0.564	0.809	0.839
ADFI, g	470.30	450.76	483.46	481.78	23	0.657	0.361	0.708
G:F, g/kg	754.99	774.81	751.70	726.71	24	0.915	0.301	0.364

¹Supplementation of 0.1% of MOS in the diet and approximately 10⁹ cfu of LM per pig was done in Phase I (days 1 to 14) and Phase II (days 15 to 28). The n = 4 replicates per treatment; there were six pigs per pen from days 0 to 14, five pigs per pen from days 14 to 21, and four pigs per pen from days 21 to 35.

²ADFI, average daily feed intake; ADG, average daily gain; BW, body weight; G:F, gain-to-feed ratio; LPS, lipopolysaccharide.

³Pooled standard error of the treatment means.

^a,bMeans within rows with different superscript are different at P ≤ 0.05.