Table 2.

Associations between plasma IL-6 level and stroke and all-cause mortality in patients with AF

Variable	Univariate Cox regression		Multivariate Cox regression
	HR (95% CI)	P-value	HR (95% CI)	P-value
Stroke
IL-6 (pg/mL)
≤55.2	Reference		Reference
>55.2	1.69 (0.61, 4.66)	0.312	3.81 (1.11, 13.05)	0.033
All-cause mortality
IL-6 (pg/mL)
≤55.2	Reference		Reference
>55.2	2.46 (1.02, 5.93)	0.045*	3.11 (1.25, 7.72)	0.015*

^*P<0.05, the difference was statistically significant.

Cox proportional hazards model for stroke adjusted for age, types of AF, history of diabetes and history of stroke; for all-cause mortality, adjusted for age, types of AF, history of coronary disease and history of heart failure; using a backward selection strategy.

AF - atrial fibrillation; CI - confidence interval; HR - hazard ratio; IL - interleukin