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. 2021 Dec 8;16(12):e0260878. doi: 10.1371/journal.pone.0260878

Fig 4. Analysis of palladin interacting proteins in PodoPalld129 mice.

Fig 4

(A) Immunofluorescence stainings of kidney sections show a reduced expression of Pdlim2 and pLasp-1 in PodoPalld129-/- mice compared with corresponding controls. No difference was found for ezrin. Scale bar represents 20 μm. (B) A significant downregulation of Pdlim2 mRNA in 6 months old PodoPalld129-/- glomeruli was found by qRT-PCR. Lasp-1 and Ezrin were not significantly changed. (C) Relative protein level in 6 months old PodoPalld129-/- glomeruli normalized to Gapdh and protein lysates of PodoPalld129+/+ glomeruli. Data are presented as means±SD; *** p<0.001; ns, not significant; unpaired Student’s t-test.